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一例口腔弹性纤维瘤样病变:临床病理分析及文献复习

A Case of an Oral Elastofibromatous Lesion: A Clinicopathological Analysis With a Literature Review.

作者信息

Ono Sawako, Masui Masanori, Obata Kyoichi, Nakamura Tomoya, Furuki Yoshihiko, Nakamura Satoko, Yamamoto Hidetaka

机构信息

Department of Pathology and Oncology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.

Department of Oral and Maxillofacial Surgery, Kagawa Prefectural Central Hospital, Takamatsu, Kagawa, Japan.

出版信息

Case Rep Dent. 2025 Jan 11;2025:5556176. doi: 10.1155/crid/5556176. eCollection 2025.

Abstract

Elastofibromatous changes of the oral mucosa, such as an elastofibroma (EF) or an elastofibromatous lesion (EFL), are not well recognized, and the second such case in Japan is reported. A 72-year-old man wearing a complete maxillary denture presented with a small nodule on the hard palate. Histopathological examination showed abundant fibrous tissue with numerous elastic fibers on Elastica van Gieson (EvG) staining. The diagnosis of an oral EFL was made. In the review of oral EF and EFL, no cases with recurrence were identified, but such lesions may resemble neoplastic lesions macroscopically. Accurate diagnosis using EvG stain is needed to recognize oral EFs and EFLs.

摘要

口腔黏膜的弹性纤维瘤样改变,如弹性纤维瘤(EF)或弹性纤维瘤样病变(EFL),尚未得到充分认识,本文报道了日本的第二例此类病例。一名佩戴全口上颌义齿的72岁男性患者硬腭出现一个小结节。组织病理学检查显示,经弹力纤维染色(EvG)后可见大量纤维组织及众多弹性纤维。诊断为口腔EFL。在对口腔EF和EFL的回顾中,未发现复发病例,但此类病变在宏观上可能类似于肿瘤性病变。需要使用EvG染色进行准确诊断以识别口腔EF和EFL。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/803b/11742071/29934be903bd/CRID2025-5556176.001.jpg

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