Sylwander Charlotte, Haglund Emma, Larsson Ingrid, Andersson Maria L E
School of Health and Welfare, Halmstad University, Halmstad, Sweden.
Spenshult Research and Development Centre, Halmstad, Sweden.
Scand J Prim Health Care. 2025 Jun;43(2):422-433. doi: 10.1080/02813432.2025.2452916. Epub 2025 Jan 20.
Knee pain increases the risk of developing chronic widespread pain (CWP) and knee osteoarthritis (KOA). The prevalence of CWP and KOA has increased, and there is a need for early prevention. Therefore, the aim was to examine the associations of health-related quality of life (HRQoL) and lifestyle habits with chronic pain at a two-year follow-up in individuals with knee pain.
A two-year longitudinal cohort study including 251 individuals aged 30-60 years reporting knee pain at baseline. HRQoL was measured via the Short-Form General Health Survey (SF-36), and lifestyle habits included questions on overweight, physical activity, diet, alcohol and tobacco use. Pain was assessed with a pain mannequin. Differences in health status and lifestyle habits over time in groups with unchanged no chronic pain (NCP), transitioned to less and more pain, and unchanged CWP were analysed using Wilcoxon's, McNemar's and Friedman's tests. Multinominal regression analysis was performed to study associations with reporting chronic pain at follow-up.
Reporting better HRQoL across various SF-36 concepts and normal weight at baseline was associated with reporting NCP after two years. A few changes were made regarding HRQoL and lifestyle habits over the course of two years, but an increase in general health was associated with transitioning to less pain.
During primary care visits for knee pain with a combination of overweight or lower HRQoL, individuals should receive comprehensive attention to prevent the development of CWP. Future studies should investigate the associations further.
膝关节疼痛会增加患慢性广泛性疼痛(CWP)和膝骨关节炎(KOA)的风险。CWP和KOA的患病率呈上升趋势,因此需要早期预防。因此,本研究旨在探讨在膝关节疼痛患者两年随访中,健康相关生活质量(HRQoL)和生活方式习惯与慢性疼痛之间的关联。
一项为期两年的纵向队列研究,纳入了251名年龄在30至60岁之间、基线时报告有膝关节疼痛的个体。通过简短通用健康调查问卷(SF-36)测量HRQoL,生活方式习惯包括有关超重、体育活动、饮食、饮酒和吸烟的问题。使用疼痛模型评估疼痛情况。对于无慢性疼痛(NCP)未改变、疼痛减轻和加重以及CWP未改变的组,分析其健康状况和生活方式习惯随时间的差异,采用Wilcoxon检验、McNemar检验和Friedman检验。进行多项回归分析以研究随访时报告慢性疼痛的相关因素。
在两年后报告NCP与在各种SF-36概念上报告更好的HRQoL以及基线时体重正常有关。在两年期间,HRQoL和生活方式习惯有一些变化,但总体健康状况的改善与疼痛减轻相关。
在因膝关节疼痛进行初级保健就诊时,若伴有超重或HRQoL较低的情况,个体应得到全面关注以预防CWP的发生。未来的研究应进一步探讨这些关联。