Papalia Rocco, Prata Francesco, Tedesco Francesco, Ragusa Alberto, Pira Matteo, Iannuzzi Andrea, Fantozzi Marco, Civitella Angelo, McGUIRE Barry, Simone Giuseppe, Scarpa Roberto M
Department of Urology, Campus Bio-Medico University Polyclinic Foundation, Rome, Italy.
Department of Urology, Campus Bio-Medico University Polyclinic Foundation, Rome, Italy -
Minerva Urol Nephrol. 2024 Dec;76(6):773-781. doi: 10.23736/S2724-6051.24.06146-9.
To report the first case series of RARC using a simplified technique for intracorporeal stentless neobladder formation.
From October 2022 to February 2023, 10 patients with high-risk bladder cancer underwent RARC at our Institution. RARC with extended pelvic lymph node dissection and totally intracorporeal neobladder using Hugo RAS system. Surgical steps of this novel reservoir are shown in the complementary video. Continuous data were presented as median and interquartile ranges (IQR) while frequencies and proportions were used to report categorical variables and compared by means of Mann-Whitney U test and Chi-square test, respectively. One-year outcomes were recorded.
All procedures were successfully performed. Median console time for neobladder configuration was 192 min (IQR, 170-219). A decrease in median operative time was observed in the second half of the series (305 vs. 322 minutes; P=0.12). Two patients (20%) experienced a minor complication (ileus and UTI, Clavien-Dindo II). At 12-months follow-up, renal function was preserved in all patients. Overall, 12-months daytime and night-time continence rates were 80% and 60%, respectively. The limited number of cases represents the main limitation of the current study.
This simplified robotic assisted intracorporeal neobladder technique demonstrates a good safety profile in this series of patients. Simplifying robotic intracorporeal surgical techniques could potentially contribute to its reproducibility and popularization in the urologic community.
报告首例采用简化技术进行体内无支架新膀胱形成的机器人辅助根治性膀胱切除术(RARC)病例系列。
2022年10月至2023年2月,10例高危膀胱癌患者在我院接受了RARC。采用Hugo RAS系统进行扩大盆腔淋巴结清扫和完全体内新膀胱的RARC。该新型储尿囊的手术步骤见补充视频。连续数据以中位数和四分位数间距(IQR)表示,频率和比例用于报告分类变量,分别采用Mann-Whitney U检验和卡方检验进行比较。记录1年的结果。
所有手术均成功完成。新膀胱构建的中位控制台时间为192分钟(IQR,170 - 219)。在该系列的后半部分观察到中位手术时间有所下降(305对322分钟;P = 0.12)。2例患者(20%)出现轻微并发症(肠梗阻和尿路感染,Clavien-Dindo II级)。在12个月的随访中,所有患者的肾功能均得以保留。总体而言,12个月时白天和夜间的控尿率分别为80%和60%。病例数量有限是本研究的主要局限性。
这种简化的机器人辅助体内新膀胱技术在该系列患者中显示出良好的安全性。简化机器人体内手术技术可能有助于其在泌尿外科领域的可重复性和推广。