Diabelková Jana, Dorko Erik, Rimárová Kvetoslava, Urdzík Peter, Sulinová Zlatana, Houžvičková Andrea, Kopecký Miroslav
Department of Public Health and Hygiene, Faculty of Medicine, Pavol Jozef Safarik University in Kosice, Kosice, Slovak Republic.
Department of Gynaecology and Obstetrics, Faculty of Medicine, Pavol Jozef Safarik University and Louis Pasteur University Hospital in Kosice, Kosice, Slovak Republic.
Cent Eur J Public Health. 2024 Dec;32(Supplement):8-11. doi: 10.21101/cejph.a8317.
Pregnancy at advanced maternal age has become more common over the last decades. Therefore, the study aimed to describe the characteristics and maternal and perinatal outcomes of women giving birth at advanced maternal age and very advanced age.
We conducted a retrospective cohort study of 2,300 singleton births that occurred in 2020-2021 at the Department of Gynaecology and Obstetrics of the Louis Pasteur University Hospital in Košice. The control (age 20-34 years), advanced maternal age (35-39 years), and very advanced maternal age (≥ 40 years) groups included 1,851, 382, and 67 women, respectively. Exclusion criteria were multiple pregnancies, maternal age less than 20 years, smoking and alcohol use, foetal malformation and intrauterine foetal death, and birth weight of 500 grams or less. Data on mothers and newborn infants have been reported from the birth book and the reports on mothers at childbirth. The data were analysed using IBM SPSS Statistics 23.0.
Our results confirmed statistically significant differences regarding the rate of preterm birth (p = 0.004), very preterm birth (p = 0.010), caesarean delivery rate (p < 0.001), very low birth weight (p = 0.027), extremely low birth weight (p = 0.001), and Apgar score at 5 minutes < 7 (p = 0.020) between newborns in the compared maternal age groups.
Advanced maternal age is a prognostic factor for poor pregnancy outcomes. Women of advanced maternal age are at higher risk of adverse obstetric and perinatal outcomes.
在过去几十年中，高龄孕产妇越来越普遍。因此，本研究旨在描述高龄和超高龄孕产妇的特征以及孕产妇和围产期结局。
我们对2020年至2021年在科希策市路易·巴斯德大学医院妇产科发生的2300例单胎分娩进行了一项回顾性队列研究。对照组（年龄20 - 34岁）、高龄孕产妇组（35 - 39岁）和超高龄孕产妇组（≥40岁）分别包括1851例、382例和67例妇女。排除标准为多胎妊娠、孕产妇年龄小于20岁、吸烟和饮酒、胎儿畸形和宫内胎儿死亡以及出生体重500克或更低。母亲和新生儿的数据来自出生记录册和分娩时母亲的报告。使用IBM SPSS Statistics 23.0对数据进行分析。
我们的结果证实，在所比较的孕产妇年龄组中，新生儿的早产率（p = 0.004）、极早产率（p = 0.010）、剖宫产率（p < 0.001）、极低出生体重率（p = 0.027）、超低出生体重率（p = 0.001）以及5分钟阿氏评分<7（p = 0.020）存在统计学上的显著差异。
高龄孕产妇是不良妊娠结局的一个预后因素。高龄孕产妇出现不良产科和围产期结局的风险更高。
