用于指导深部脑刺激治疗干预的电生理方法。
Electrophysiological approaches to informing therapeutic interventions with deep brain stimulation.
作者信息
Asadi Atefeh, Wiesman Alex I, Wiest Christoph, Baillet Sylvain, Tan Huiling, Muthuraman Muthuraman
机构信息
Neural Engineering with Signal Analytics and Artificial Intelligence, Department of Neurology, University Clinic Würzburg, Würzburg, Germany.
Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, BC, Canada.
出版信息
NPJ Parkinsons Dis. 2025 Jan 20;11(1):20. doi: 10.1038/s41531-024-00847-3.
Neuromodulation therapy comprises a range of non-destructive and adjustable methods for modulating neural activity using electrical stimulations, chemical agents, or mechanical interventions. Here, we discuss how electrophysiological brain recording and imaging at multiple scales, from cells to large-scale brain networks, contribute to defining the target location and stimulation parameters of neuromodulation, with an emphasis on deep brain stimulation (DBS).
神经调节疗法包括一系列使用电刺激、化学药剂或机械干预来调节神经活动的非破坏性且可调节的方法。在此，我们将讨论从细胞到大规模脑网络的多尺度电生理脑记录和成像如何有助于确定神经调节的目标位置和刺激参数，重点是深部脑刺激（DBS）。
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