Zhou Siyu, Zhang Yuan, He Huijuan, Wang Xiangrong, Li Mengying, Zhang Na, Song Jiali
School of Nursing, Hubei University of Chinese Medicine, No. 16 Huangjiahu Lake Road, Hongshan District, Wuhan City, 430065, Hubei Province, China.
Nursing Department, Zhongnan Hospital of Wuhan University, Wuhan City, China.
Sci Rep. 2025 Jan 20;15(1):2539. doi: 10.1038/s41598-024-84642-3.
The symptoms of stroke jeopardize patients' health and increase the burden on society and caregivers. Although the traditional symptom cluster research paradigm can enhance management efficiency, it fails to provide targets for intervention, thereby hindering the development of patient-centered precision medicine. However, the symptom network paradigm, as a novel research approach, addresses the limitations of traditional symptom management by identifying core symptoms and determining intervention targets, thereby enhancing the efficiency and precision of symptom management. This study. aims to explore the symptom network and core symptoms of acute-phase stroke patients. A convenience sample of 505 stroke patients was selected for this study. Symptoms were assessed by the Stroke Symptom Experience Scale.Exploratory factor analysis was utilized to extract symptom clusters, and network analysis was conducted to construct the symptom network and characterize its nodes. In this study, four symptom clusters were extracted through exploratory factor analysis. Based on the results of node predictability(re) and node centrality such as strength centrality (rs), it was found that the symptoms of "No interest in surroundings" (rs = 1.299, re = 1.081), "Be disappointed about future" (rs = 0.922, re = 0.901), and "Unable to maintain body balance" (rs = 0.747, re = 0.744) had the highest centrality and predictability values, indicating their core positions within the symptom network. No interest in surroundings, Be disappointed about future, and Unable to maintain body balance are core symptoms in the symptom network. In the future, intervention methods for core symptoms can be constructed and validated for their intervention effects to further demonstrate the benefits of core symptoms.
中风症状危及患者健康,增加社会和护理人员负担。尽管传统症状群研究范式可提高管理效率,但未能提供干预靶点,从而阻碍了以患者为中心的精准医学发展。然而,症状网络范式作为一种新颖的研究方法,通过识别核心症状和确定干预靶点,解决了传统症状管理的局限性,从而提高了症状管理的效率和精准度。本研究旨在探索急性期中风患者的症状网络和核心症状。本研究选取了505例中风患者的便利样本。通过中风症状体验量表评估症状。利用探索性因素分析提取症状群,并进行网络分析以构建症状网络并表征其节点。在本研究中,通过探索性因素分析提取了四个症状群。根据节点可预测性(re)和节点中心性如强度中心性(rs)的结果,发现“对周围环境无兴趣”(rs = 1.299,re = 1.081)、“对未来感到失望”(rs = 0.922,re = 0.901)和“无法保持身体平衡”(rs = 0.747,re = 0.744)的症状具有最高的中心性和可预测性值,表明它们在症状网络中的核心地位。对周围环境无兴趣、对未来感到失望和无法保持身体平衡是症状网络中的核心症状。未来,可以构建针对核心症状的干预方法并验证其干预效果,以进一步证明核心症状的益处。