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五行音乐疗法对脑卒中后抑郁的疗效：一项系统评价与Meta分析

The effectiveness of five-element music therapy for post-stroke depression: A systematic review and meta-analysis.

作者信息

Zhong Kelong, An Xuemei, Kong Yun

机构信息

Chengdu University of Traditional Chinese Medicine, China.

Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, China.

出版信息

Heliyon. 2024 Feb 17;10(5):e26603. doi: 10.1016/j.heliyon.2024.e26603. eCollection 2024 Mar 15.

DOI:10.1016/j.heliyon.2024.e26603
PMID:38444465
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10912230/
Abstract

INTRODUCTION

Five-element music therapy is widely utilized as a complementary approach in stroke rehabilitation, particularly for addressing post-stroke depression (PSD). This study systematically evaluates the clinical impact of five-element music therapy on individuals experiencing PSD.

METHODS

A comprehensive search of nine electronic databases, encompassing published and unpublished gray literature up to February 15, 2022, was conducted. Two investigators independently reviewed and extracted data, evaluating bias risk according to predefined criteria. Meta-analysis was performed using RevMan 5.4 software.

RESULTS

Inclusive of 20 studies involving 1561 individuals with PSD, the meta-analysis revealed a significant difference in favor of five-element music therapy for relieving depression (standardized mean difference [SMD] = -1.07, 95% confidence interval [CI]: -1.34 to -0.81,  < 0.00001), improving daily living abilities (SMD = 2.49, 95% CI 1.00 to 3.98,  < 0.00001), and elevating serum 5-hydroxytryptamine(5-HT) levels (SMD = 0.87, 95% CI 0.56 to 1.17,  < 0.00001).

CONCLUSION

Five-element music therapy demonstrated efficacy in improving depressive symptoms, daily living skills, and serum 5-HT levels in individuals experiencing PSD.The review was registered on International Prospective Register of Systematic Reviews (registration number CRD 42022332282).

摘要

介绍

五音疗法作为一种辅助方法在中风康复中被广泛应用，尤其是用于治疗中风后抑郁（PSD）。本研究系统评估了五音疗法对PSD患者的临床影响。

方法

对九个电子数据库进行全面检索，涵盖截至2022年2月15日已发表和未发表的灰色文献。两名研究者独立审查并提取数据，根据预定义标准评估偏倚风险。使用RevMan 5.4软件进行荟萃分析。

结果

纳入20项研究，共1561例PSD患者，荟萃分析显示五音疗法在缓解抑郁方面有显著差异（标准化均数差[SMD]= -1.07，95%置信区间[CI]：-1.34至-0.81，P<0.00001），在改善日常生活能力方面有显著差异（SMD = 2.49，95% CI 1.00至3.98，P<0.00001），在提高血清5-羟色胺（5-HT）水平方面有显著差异（SMD = 0.87，95% CI 0.56至1.17，P<0.00001）。

结论

五音疗法在改善PSD患者的抑郁症状、日常生活技能和血清5-HT水平方面显示出疗效。该综述已在国际系统评价前瞻性注册库注册（注册号CRD 42022332282）。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/924a/10912230/187e01c1bd11/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/924a/10912230/6051419bf422/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/924a/10912230/0b919738eae2/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/924a/10912230/dd390a04ac2b/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/924a/10912230/9733efea3ad1/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/924a/10912230/98915e865666/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/924a/10912230/3b9eafaec88b/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/924a/10912230/187e01c1bd11/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/924a/10912230/6051419bf422/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/924a/10912230/0b919738eae2/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/924a/10912230/dd390a04ac2b/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/924a/10912230/9733efea3ad1/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/924a/10912230/98915e865666/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/924a/10912230/3b9eafaec88b/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/924a/10912230/187e01c1bd11/gr7.jpg

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