Alkhemeiri Aysha, El-Khatib Ziad, Alameri Abrar Hassan, AlKaabi Athari Ahmed, Lakshmanan Jeyaseelan, Awofeso Niyi
Department of Medicine, Sheikh Tahnoun Bin Mohammed Medical City, Alain, United Arab Emirates.
Department of Global Public Health, Karolinska Institute, Stockholm, Sweden.
J Epidemiol Glob Health. 2025 Jan 20;15(1):6. doi: 10.1007/s44197-025-00346-5.
A substantial subset of individuals recovering from the Coronavirus disease 2019 (COVID-19) continues to experience persistent symptoms. Individuals with type 2 diabetes face increased morbidity and mortality following COVID-19 infection. This study aimed to identify risk factors for developing post-COVID-19 conditions among COVID-19 patients with diabetes compared to those without diabetes in the United Arab Emirates.
A retrospective study was conducted on a random sample of 400 patients with confirmed COVID-19 (n = 200/400 patients with diabetes versus n = 200 patients without diabetes). Participants were invited to a telephone interview to assess post-COVID-19 symptoms persisting for at least three months after their initial positive COVID-19 polymerase chain reaction (PCR) test. A total of 167 hospitalized patients participated, including 89 with pre-existing diabetes and 78 without diabetes.
The prevalence of self-reported post-COVID-19 conditions among participants with diabetes was 34.9%, compared to 14.1% among those without diabetes. Patients with diabetes reported a significant decline in functional status post-COVID-19, with 34.8% experiencing impaired physical activity and 32.6% reporting pain and discomfort, compared to 15.4% and 11.5%, respectively, among participants without diabetes. Older age and female gender were associated with a higher prevalence of post-COVID-19 conditions in the diabetes group.
Patients with diabetes in this study self-reported a higher frequency and severity of post-COVID-19 conditions compared to those without diabetes. Risk factors predisposing to severe post-COVID-19 conditions included female gender, older age, and comorbidities. Self-reported depression was rare in both groups of this cohort.
相当一部分从2019年冠状病毒病(COVID-19)中康复的个体仍持续出现症状。2型糖尿病患者在感染COVID-19后发病率和死亡率增加。本研究旨在确定阿拉伯联合酋长国患有糖尿病的COVID-19患者与未患糖尿病的患者相比,发生COVID-19后状况的危险因素。
对400例确诊COVID-19的患者进行了一项回顾性研究(n = 200/400例糖尿病患者与n = 200例无糖尿病患者)。邀请参与者进行电话访谈,以评估在首次COVID-19聚合酶链反应(PCR)检测呈阳性后持续至少三个月的COVID-19后症状。共有167名住院患者参与,其中89名患有糖尿病,78名无糖尿病。
糖尿病参与者中自我报告的COVID-19后状况患病率为34.9%,而无糖尿病者为14.1%。糖尿病患者报告COVID-19后功能状态显著下降,34.8%的患者身体活动受损,32.6%的患者报告疼痛和不适,相比之下,无糖尿病参与者中这一比例分别为15.4%和11.5%。在糖尿病组中,年龄较大和女性与COVID-19后状况的较高患病率相关。
本研究中,与无糖尿病的患者相比,糖尿病患者自我报告的COVID-19后状况的频率和严重程度更高。导致严重COVID-19后状况的危险因素包括女性、年龄较大和合并症。在该队列的两组中,自我报告的抑郁症都很少见。