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注意力缺陷多动障碍(ADHD)中的上角膜圆锥:一例报告及文献综述

Superior Keratoconus in Attention-Deficit Hyperactivity Disorder (ADHD): A Case Report and Literature Review.

作者信息

Assayag Elishai, Zadok David, Carmel Moshe, Abulafia Adi, Weill Yishay

机构信息

Department of Ophthalmology, Shaare Zedek Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, ISR.

出版信息

Cureus. 2024 Dec 19;16(12):e76013. doi: 10.7759/cureus.76013. eCollection 2024 Dec.

DOI:10.7759/cureus.76013
PMID:39835030
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11743682/
Abstract

Keratoconus is a progressive corneal ectasia that may lead to severe visual impairment. Superior keratoconus (SK) is an uncommon form of the disease, and few cases have been reported thus far. We present an unusual SK case and a literature review of this rare diagnosis. A 49-year-old man presented to the ophthalmology clinic complaining of decreased vision in his right eye. Previous medical and ocular histories included medically treated attention-deficit hyperactivity disorder (ADHD) and keratoconus, which were diagnosed only in adulthood. A dense posterior subcapsular cataract was observed in the right eye. Corneal tomography revealed bilateral asymmetric SK, which was more severe in the right eye. The patient demonstrated unique eye-rubbing habits, which helped him cope with his ADHD symptoms and correlated with the keratoconus severity in each eye. In a literature review, 11 previously published cases of SK were summarized, none of which were associated with ADHD or included ipsilateral cataracts as in our patient. In conclusion, ADHD may cause repetitive eye rubbing and subsequent uncommon corneal ectatic changes, such as SK. Early recognition and characterization of eye rubbing can be crucial in detecting coexisting mental and ocular disorders.

摘要

圆锥角膜是一种进行性角膜扩张疾病,可导致严重视力损害。上角膜圆锥(SK)是该疾病的一种罕见形式,迄今为止报道的病例很少。我们报告一例不寻常的SK病例,并对这一罕见诊断进行文献综述。一名49岁男性到眼科门诊就诊,主诉右眼视力下降。既往病史和眼部病史包括药物治疗的注意力缺陷多动障碍(ADHD)和圆锥角膜,均在成年期才被诊断出来。右眼观察到致密的后囊下白内障。角膜地形图显示双侧不对称SK,右眼更为严重。患者表现出独特的揉眼习惯,这有助于他应对ADHD症状,且与每只眼睛的圆锥角膜严重程度相关。在文献综述中,总结了11例先前发表的SK病例,其中没有一例与ADHD相关,也没有像我们的患者那样包括同侧白内障。总之,ADHD可能导致反复揉眼及随后出现罕见的角膜扩张性改变,如SK。早期识别和明确揉眼情况对于发现并存的精神和眼部疾病可能至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a070/11743682/ccb08b495730/cureus-0016-00000076013-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a070/11743682/ccb08b495730/cureus-0016-00000076013-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a070/11743682/ccb08b495730/cureus-0016-00000076013-i01.jpg

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Cureus. 2024 Dec 19;16(12):e76013. doi: 10.7759/cureus.76013. eCollection 2024 Dec.
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本文引用的文献

1
Modeling biological growth of human keratoconus: On the effect of tissue degradation, location and size.建模人眼角膜圆锥的生物生长:组织降解、位置和大小的影响。
Comput Biol Med. 2024 Sep;180:108976. doi: 10.1016/j.compbiomed.2024.108976. Epub 2024 Aug 9.
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Psychiatric Comorbidities Associated With Keratoconus.与圆锥角膜相关的精神共病。
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Keratoconus: An updated review.圆锥角膜:更新综述。
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The Prevalence and Risk Factors for Keratoconus: A Systematic Review and Meta-Analysis.圆锥角膜的患病率及危险因素:系统评价和荟萃分析。
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The genetic and environmental factors for keratoconus.圆锥角膜的遗传和环境因素。
Biomed Res Int. 2015;2015:795738. doi: 10.1155/2015/795738. Epub 2015 May 17.
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Bilateral superior keratoconus: two case reports.双侧圆锥角膜:两例病例报告
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Superior keratoconus with hydrops.伴有角膜膨隆的重度圆锥角膜
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Superior keratoconus with inferior paracentral corneal thinning and inferior peripheral pellucid marginal degeneration.
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