Jing Jiapeng, Zheng Qinzhi, Dong Hongfei, Wang Yan, Wang Peiji, Fan Di, Xu Zhuo
Department of Rehabilitation, China-Japan Union Hospital of Jilin University, Changchun, China.
Rehabilitation Therapeutics, School of Nursing, Jilin University, Changchun, China.
Front Physiol. 2025 Jan 6;15:1488305. doi: 10.3389/fphys.2024.1488305. eCollection 2024.
Low load resistance training with blood flow restriction (LL-BFRT) has been shown to improve muscle strength and hypertrophic function. The effect of LL-BFRT on lower extremity muscle improvement has been widely discussed. However, no studies have discussed the effect of this training method on the upper extremity muscles until now. This systematic review and meta-analysis focused on the use of LL-BFRT in the upper extremity muscles.
The relevant literature was searched in four major databases including Pubmed, Web of science, the Cochrane Library and Embase from 10 June 2024. The Cochrane Collaboration's tool and GRADE methodology were used to assess the risk of bias and quality in included studies.
The meta-analysis included a total of 11 articles with 220 participants. LL-BFRT and high load resistance training (HLRT) produced similar effects in improving upper extremity muscle strength (low certainty evidence, SMD: -0.35; 95%CI: -0.73 to 0.03; : 0.07; I: 2%) and hypertrophy (moderate certainty evidence, SMD: -0.36; 95%CI: -0.73 to 0.01; : 0.05; I: 0%). Compared with low load resistance training (LLRT), LL-BFRT showed greater advantages in improving upper extremity muscle strength (low certainty evidence, SMD: 0.67; 95%CI: 0.33 to 1.01; : 0.0001; I: 0%) and hypertrophy (low certainty evidence, SMD: 0.37; 95%CI: 0.06 to 0.67; : 0.02; I: 0%).
In general, LL-BFRT can be used as an alternative training method for HLRT to improve upper extremity muscle strength and hypertrophy. Our study shows that the effect of LL-BFRT on upper extremity muscle is limited by age and region. It is necessary to formulate reasonable exercise programs according to the characteristics of different demographic groups.
https://www.crd.york.ac.uk/PROSPERO/, identifier CRD42024555514.
低负荷血流限制抗阻训练（LL-BFRT）已被证明可改善肌肉力量和肥大功能。LL-BFRT对下肢肌肉改善的效果已得到广泛讨论。然而，到目前为止，尚无研究讨论这种训练方法对上肢肌肉的影响。本系统评价和荟萃分析聚焦于LL-BFRT在上肢肌肉中的应用。
于2024年6月10日在四个主要数据库（包括PubMed、科学网、考克兰图书馆和Embase）中检索相关文献。采用考克兰协作网工具和GRADE方法评估纳入研究的偏倚风险和质量。
荟萃分析共纳入11篇文章，220名参与者。LL-BFRT和高负荷抗阻训练（HLRT）在改善上肢肌肉力量方面产生相似效果（低确定性证据，标准化均数差：-0.35；95%置信区间：-0.73至0.03；P：0.07；I²：2%）和肥大（中度确定性证据，标准化均数差：-0.36；95%置信区间：-0.73至0.01；P：0.05；I²：0%）。与低负荷抗阻训练（LLRT）相比，LL-BFRT在改善上肢肌肉力量（低确定性证据，标准化均数差：0.67；95%置信区间：0.33至1.01；P：0.0001；I²：0%）和肥大（低确定性证据，标准化均数差：0.37；95%置信区间：0.06至0.67；P：0.02；I²：0%）方面显示出更大优势。
总体而言，LL-BFRT可作为HLRT的替代训练方法来改善上肢肌肉力量和肥大。我们的研究表明，LL-BFRT对上肢肌肉的影响受年龄和部位限制。有必要根据不同人群特征制定合理的运动方案。
