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来自坦桑尼亚北部的巨大胸腰骶部脊髓脊膜膨出:病例报告

A Large Thoracolumbosacral Meningomyelocele From Northern Tanzania: A Case Report.

作者信息

Suleman Mujaheed, Rabiel Happiness, Vaughan Kerry, Shadrack Mathayo, Ndibalema Goodluck, Lodhia Raghav, Lodhia Jay

机构信息

Department of General Surgery, Kilimanjaro Christian Medical Centre, Moshi PO Box 3010, Tanzania.

Department of Neurosurgery, Kilimanjaro Christian Medical Centre, Moshi PO Box 3310, Tanzania.

出版信息

Case Rep Surg. 2025 Jan 9;2025:5662565. doi: 10.1155/cris/5662565. eCollection 2025.

DOI:10.1155/cris/5662565
PMID:39835283
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11745552/
Abstract

Meningomyelocele and meningocele are types of neural tube defects, which are congenital abnormalities of the spine and spinal cord. These conditions are frequently encountered by pediatric neurosurgeons worldwide and represent a significant public health concern due to their association with a range of collateral conditions, other malformations, and increased morbidity. While many cases can be identified during prenatal ultrasound screenings, this is often challenging in resource-limited settings with poor health-seeking behaviors. Surgical intervention is the primary treatment for these defects, and while various methods are described in the literature, larger defects require complex flaps and techniques, with limited options available. Beyond early surgical intervention, patients require lifelong care involving multidisciplinary medical teams.

摘要

脊髓脊膜膨出和脊膜膨出是神经管缺陷的类型,是脊柱和脊髓的先天性异常。全球的儿科神经外科医生经常遇到这些情况,由于它们与一系列附带病症、其他畸形以及发病率增加有关,因此是一个重大的公共卫生问题。虽然许多病例可以在产前超声筛查中被识别出来,但在医疗寻求行为不佳的资源有限环境中,这往往具有挑战性。手术干预是这些缺陷的主要治疗方法,虽然文献中描述了各种方法,但较大的缺陷需要复杂的皮瓣和技术,可用的选择有限。除了早期手术干预外,患者还需要多学科医疗团队的终身护理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db31/11745552/04be77490512/CRIS2025-5662565.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db31/11745552/79c89f7b2d66/CRIS2025-5662565.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db31/11745552/b5273e0c34fc/CRIS2025-5662565.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db31/11745552/5498bd296cac/CRIS2025-5662565.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db31/11745552/04be77490512/CRIS2025-5662565.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db31/11745552/79c89f7b2d66/CRIS2025-5662565.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db31/11745552/b5273e0c34fc/CRIS2025-5662565.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db31/11745552/5498bd296cac/CRIS2025-5662565.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db31/11745552/04be77490512/CRIS2025-5662565.004.jpg

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A Large Thoracolumbosacral Meningomyelocele From Northern Tanzania: A Case Report.来自坦桑尼亚北部的巨大胸腰骶部脊髓脊膜膨出:病例报告
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本文引用的文献

1
Double Lumbar Localization of Myelomeningocele: Case Report.脊髓脊膜膨出的双腰椎定位:病例报告。
Pediatr Neurosurg. 2023;58(2):97-104. doi: 10.1159/000530726. Epub 2023 Apr 19.
2
Experience of 300 cases of prenatal fetoscopic open spina bifida repair: report of the International Fetoscopic Neural Tube Defect Repair Consortium.300 例产前经镜开放性脊柱裂修复经验:国际经镜神经管缺陷修复联盟报告。
Am J Obstet Gynecol. 2021 Dec;225(6):678.e1-678.e11. doi: 10.1016/j.ajog.2021.05.044. Epub 2021 Jun 3.
3
A Practical Approach to Diagnosis of Spinal Dysraphism.
脊髓发育异常诊断的实用方法
Radiographics. 2021 Mar-Apr;41(2):559-575. doi: 10.1148/rg.2021200103. Epub 2021 Jan 15.
4
Prevalence of Spina Bifida among Newborns in Africa: A Systematic Review and Meta-Analysis.非洲新生儿脊柱裂的患病率:一项系统评价和荟萃分析。
Scientifica (Cairo). 2020 Oct 6;2020:4273510. doi: 10.1155/2020/4273510. eCollection 2020.
5
Co-morbidities Associated With Early Mortality in Adults With Spina Bifida.合并症与成人脊柱裂患者早期死亡率的相关性。
Am J Phys Med Rehabil. 2018 Dec;97(12):861-865. doi: 10.1097/PHM.0000000000000964.
6
Reverse U-shaped horseshoe kidney accompanied by gibbus deformity and spina bifida.伴有脊柱后凸畸形和脊柱裂的反向U形马蹄肾。
Jpn J Radiol. 2016 Jun;34(6):448-50. doi: 10.1007/s11604-016-0536-4. Epub 2016 Apr 25.
7
Bilateral split latissimus dorsi V-Y flaps for closure of large thoracolumbar meningomyelocele defects.双侧劈开背阔肌V-Y皮瓣用于闭合胸腰段脊髓脊膜膨出大缺损。
Br J Plast Surg. 2003 Apr;56(3):303-6. doi: 10.1016/s0007-1226(03)00115-2.