Marcus J, Hans S L, Lewow E, Wilkinson L, Burack C M
Schizophr Bull. 1985;11(1):85-100. doi: 10.1093/schbul/11.1.85.
The results of the two neurological examinations of the Israeli children, both original and followup, are presented. The multidimensional scalogram analysis technique was used to identify children with multiple areas of neurological dysfunction. These children consisted almost exclusively of the offspring of schizophrenic patients: 22 of the 50 index cases were in this region of poor functioning during at least one of the testing periods, as compared with only 3 of the 50 control cases. The most common neurological signs were "soft" perceptual-sensory signs, poor motor coordination, poor right-left orientation, poor balance, and motor overflow. No "hard" neurological differences were found between the groups. This is the first major report of long-term stability of neurological soft signs in the offspring of schizophrenic persons.
本文呈现了对以色列儿童进行的两次神经学检查结果，包括初次检查和后续检查。采用多维标度分析技术来识别存在多个神经功能障碍区域的儿童。这些儿童几乎全部是精神分裂症患者的后代：在至少一个测试阶段，50例索引病例中有22例处于该功能不良区域，相比之下，50例对照病例中只有3例。最常见的神经学体征为“软性”感知觉体征、运动协调性差、左右定向能力差、平衡能力差以及运动泛化。两组之间未发现“硬性”神经学差异。这是关于精神分裂症患者后代神经软性体征长期稳定性的首份主要报告。
