渗透素与回肠溃疡：一例报告

Osmosin and ileal ulceration: a case report.

作者信息

Cree I A, Walker M A, Wright M, Forrester J C

出版信息

Scott Med J. 1985 Jan;30(1):40-1. doi: 10.1177/003693308503000109.

Abstract

A 78-year-old woman presented with an acute abdomen and was found to have a perforation of her terminal ileum. She did not survive the post-operative period and at necropsy was found to have numerous ulcers of the ileum. In the ulcerated areas there was a transmural chronic inflammatory infiltrate, but no evidence of granulomata. We believe that this ulceration was caused by ingestion of Osmosin tablets containing indomethacin and suggest a possible pathogenesis.

摘要

一名78岁女性因急腹症就诊，检查发现其回肠末端穿孔。她术后未能存活，尸检发现回肠有多处溃疡。在溃疡区域有透壁性慢性炎性浸润，但无肉芽肿证据。我们认为这种溃疡是由摄入含吲哚美辛的奥索辛片引起的，并提出了一种可能的发病机制。