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回肠末端穿孔:尼可地尔治疗的一种可能并发症。

Perforation of the terminal ileum: a possible complication of nicorandil therapy.

作者信息

King P M, Suttie S A, Jansen J O, Watson A J M

机构信息

Department of Surgery, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, AB25 2ZN, UK.

出版信息

Surgeon. 2004 Feb;2(1):56-7. doi: 10.1016/s1479-666x(04)80140-9.

DOI:10.1016/s1479-666x(04)80140-9
PMID:15570809
Abstract

Recent reports have implicated nicorandil as a possible causative agent in the pathogenesis of anal and oral ulceration. We report a case of ulceration and perforation of the terminal ileum in a patient taking nicorandil. The possibility of an association between nicorandil therapy and gastrointestinal ulceration is discussed.

摘要

近期报告显示,尼可地尔可能是导致肛门和口腔溃疡发病的病因。我们报告了1例服用尼可地尔的患者发生回肠末端溃疡和穿孔的病例。本文讨论了尼可地尔治疗与胃肠道溃疡之间存在关联的可能性。

相似文献

1
Perforation of the terminal ileum: a possible complication of nicorandil therapy.回肠末端穿孔:尼可地尔治疗的一种可能并发症。
Surgeon. 2004 Feb;2(1):56-7. doi: 10.1016/s1479-666x(04)80140-9.
2
Nicorandil associated anal ulceration.尼可地尔相关性肛门溃疡
Colorectal Dis. 2004 Nov;6(6):527. doi: 10.1111/j.1463-1318.2004.00721.x.
3
Nicorandil associated colonic ulceration: case series of an increasingly recognized complication.尼可地尔相关性结肠溃疡:一种日益被认识到的并发症的病例系列。
Dig Dis Sci. 2011 Aug;56(8):2404-8. doi: 10.1007/s10620-011-1634-x. Epub 2011 Mar 6.
4
Colonic and parastomal ulceration related to nicorandil.与尼可地尔相关的结肠及造口旁溃疡
Surg Laparosc Endosc Percutan Tech. 2011 Jun;21(3):e132-3. doi: 10.1097/SLE.0b013e3182155ea9.
5
Anal ulceration associated with Nicorandil: case series and review of the literature.与尼可地尔相关的肛门溃疡:病例系列及文献综述
Colorectal Dis. 2006 Oct;8(8):717-20. doi: 10.1111/j.1463-1318.2006.00972.x.
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Use of nicorandil is Associated with Increased Risk for Gastrointestinal Ulceration and Perforation- A Nationally Representative Population-based study.尼可地尔的使用与胃肠道溃疡和穿孔风险增加相关——一项基于全国代表性人群的研究。
Sci Rep. 2015 Jun 29;5:11495. doi: 10.1038/srep11495.
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Nicorandil: do the dermatological and gastrointestinal risks outweigh the benefits?尼可地尔:皮肤和胃肠道风险是否超过获益?
Br J Dermatol. 2012 Nov;167(5):1048-52. doi: 10.1111/j.1365-2133.2012.11185.x. Epub 2012 Oct 5.
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Ulceration of the nasal dorsum: a rare cause?鼻背溃疡:一种罕见病因?
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Nicorandil-induced terminal ileal ulceration--a probable link.尼可地尔诱发的回肠末端溃疡——一种可能的联系。
BMJ Case Rep. 2010 May 31;2010:bcr09.2009.2303. doi: 10.1136/bcr.09.2009.2303.
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Nicorandil induced oral ulceration.尼可地尔诱发口腔溃疡。
Aust Fam Physician. 2003 Jun;32(6):452-3.

引用本文的文献

1
Nicorandil-induced ulcerations: a 10-year observational study of all cases spontaneously reported to the French pharmacovigilance network.尼可地尔诱导性溃疡:法国药物警戒网络自发报告的所有病例的 10 年观察性研究。
Int Wound J. 2018 Aug;15(4):508-518. doi: 10.1111/iwj.12845. Epub 2018 May 16.
2
Use of nicorandil is Associated with Increased Risk for Gastrointestinal Ulceration and Perforation- A Nationally Representative Population-based study.尼可地尔的使用与胃肠道溃疡和穿孔风险增加相关——一项基于全国代表性人群的研究。
Sci Rep. 2015 Jun 29;5:11495. doi: 10.1038/srep11495.
3
Nicorandil-induced colonic ulceration.
尼可地尔诱发的结肠溃疡
BMJ Case Rep. 2015 Feb 20;2015:bcr2014205310. doi: 10.1136/bcr-2014-205310.
4
Nicorandil-induced terminal ileal ulceration--a probable link.尼可地尔诱发的回肠末端溃疡——一种可能的联系。
BMJ Case Rep. 2010 May 31;2010:bcr09.2009.2303. doi: 10.1136/bcr.09.2009.2303.
5
Nicorandil: from ulcer to fistula into adjacent organs.尼可地尔:从溃疡到瘘管再到邻近器官。
Int Wound J. 2013 Apr;10(2):210-3. doi: 10.1111/j.1742-481X.2012.00966.x. Epub 2012 Mar 28.
6
Nicorandil associated colonic ulceration: case series of an increasingly recognized complication.尼可地尔相关性结肠溃疡:一种日益被认识到的并发症的病例系列。
Dig Dis Sci. 2011 Aug;56(8):2404-8. doi: 10.1007/s10620-011-1634-x. Epub 2011 Mar 6.
7
Rectal ulceration caused by the anti-anginal nicorandil: Case report of a preventable complication.抗心绞痛药物尼可地尔引起的直肠溃疡:一例可预防并发症的病例报告
Patient Saf Surg. 2010 Jun 30;4(1):10. doi: 10.1186/1754-9493-4-10.
8
Persistent orocutaneous and anal fistulae induced by nicorandil: a case report.尼可地尔诱发的持续性口皮肤瘘和肛瘘:一例报告
J Med Case Rep. 2009 Nov 12;3:119. doi: 10.1186/1752-1947-3-119.
9
Nicorandil-induced severe perianal ulceration.
Tech Coloproctol. 2007 Dec;11(4):343-5. doi: 10.1007/s10151-007-0378-2. Epub 2007 Dec 3.
10
Anal ulceration induced by nicorandil.尼可地尔诱发的肛门溃疡
BMJ. 2007 Nov 3;335(7626):936-7. doi: 10.1136/bmj.39246.714896.BE.