微小RNA荣获重大奖项。
MicroRNA Gets a Mighty Award.
作者信息
Li Yu, Chen Sijie, Rao Hai, Cui Shengjin, Chen Guoan
机构信息
Department of Human Cell Biology and Genetics, Joint Laboratory of Guangdong-Hong Kong Universities for Vascular Homeostasis and Diseases, School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, 518055, China.
Department of Biochemistry, Key University Laboratory of Metabolism and Health of Guangdong, School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, 518055, China.
出版信息
Adv Sci (Weinh). 2025 Feb;12(7):e2414625. doi: 10.1002/advs.202414625. Epub 2025 Jan 21.
Recent advancements in microRNAs (miRNAs) research have revealed their key roles in both normal physiological processes and pathological conditions, leading to potential applications in diagnostics and therapeutics. However, the path forward is fraught with several scientific and technical challenges. This review article briefly explores the milestones of the discovery, biogenesis, functions, and application for clinical diagnostic and therapeutic strategies of miRNAs. The potential challenges and future directions are also discussed to fully harness their capabilities.
微小RNA（miRNA）研究的最新进展揭示了它们在正常生理过程和病理状况中的关键作用，从而在诊断和治疗方面具有潜在应用。然而，前进的道路充满了若干科学和技术挑战。这篇综述文章简要探讨了miRNA发现、生物发生、功能以及临床诊断和治疗策略应用方面的里程碑。还讨论了潜在挑战和未来方向，以充分利用它们的能力。
Zotero 插件