原发性肺癌和孤立性脑转移瘤的外科治疗。
Surgical treatment of primary lung cancer and solitary brain metastasis.
作者信息
Mussi A, Janni A, Pistolesi M, Ravelli V, Buonaguidi R, Angeletti C A
出版信息
Thorax. 1985 Mar;40(3):191-3. doi: 10.1136/thx.40.3.191.
Twenty patients with carcinoma of the lung and a brain metastasis have undergone combined lung and brain surgery, which was synchronous in five. There were no operative deaths. Survival from the first surgical intervention was less than one year (3-10 months) in four patients (20%), one to two years in four (20%) and more than two years (26-66 months) in five patients (25%). Seven patients (35%) are alive and well after an average period of three years and three months (15-66 months). Actuarial survival at five years is 33.6%. All patients had severe neurological symptoms and 18 (90%) had a complete remission. Our experience and data reported in the literature point to the effectiveness of combined lung and brain surgery in prolonging symptom free survival in patients with lung cancer and solitary brain metastasis.
20例肺癌伴脑转移患者接受了肺和脑联合手术，其中5例为同期手术。无手术死亡病例。首次手术干预后的生存时间：4例患者（20%）不足1年（3 - 10个月），4例患者（20%）为1至2年，5例患者（25%）超过2年（26 - 66个月）。7例患者（35%）在平均3年3个月（15 - 66个月）后仍存活且状况良好。5年精算生存率为33.6%。所有患者均有严重神经症状，18例（90%）完全缓解。我们的经验以及文献报道的数据表明，肺和脑联合手术对于延长肺癌伴孤立性脑转移患者的无症生存期有效。
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