Zhang Pei-Pei, Li Liang, Qu Hao-Yu, Chen Guang-Yu, Xie Meng-Zhou, Chen Yan-Kun
School of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha 410200, Hunan Province, China.
Hunan Engineering Technology Research Center for Medicinal and Functional Food, Hunan University of Chinese Medicine, Changsha 410200, Hunan Province, China.
World J Gastroenterol. 2025 Jan 21;31(3):96582. doi: 10.3748/wjg.v31.i3.96582.
-associated gastritis (HPAG) is a common condition of the gastrointestinal tract. However, extensive and long-term antibiotic use has resulted in numerous adverse effects, including increased resistance, gastrointestinal dysfunction, and increased recurrence rates. When these concerns develop, traditional Chinese medicine (TCM) may have advantages. TCM is based on the concept of completeness and aims to eliminate pathogens and strengthen the body. It has the potential to prevent this condition while also boosting the rate of eradication. This review elaborates on the mechanism of TCM treatment for HPAG based on cellular signalling pathways, which reflects the flexibility of TCM in treating diseases and the advantages of multi-level, multi-pathway, and multi-target treatments for HPAG.
幽门螺杆菌相关性胃炎（HPAG）是一种常见的胃肠道疾病。然而，广泛长期使用抗生素已导致诸多不良反应，包括耐药性增加、胃肠功能紊乱以及复发率上升。当出现这些问题时，中医可能具有优势。中医基于整体观念，旨在祛邪扶正。它有预防这种疾病的潜力，同时还能提高根除率。本综述基于细胞信号通路阐述了中医治疗HPAG的机制，这体现了中医在治疗疾病方面的灵活性以及对HPAG进行多层次、多途径、多靶点治疗的优势。
