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Finite element models of intervertebral disc: recent advances and prospects.

作者信息

Sun Tianze, Wang Junlin, Liu Xin, Huang Huagui, Wang Jinzuo, Suo Moran, Zhang Jing, Li Zhonghai

机构信息

Department of Orthopedics, First Affiliated Hospital of Dalian Medical University, Dalian, The People's Republic of China.

Key Laboratory of Molecular Mechanism for Repair and Remodeling of Orthopedic Diseases, Liaoning Province, Dalian, The People's Republic of China.

出版信息

Ann Med. 2025 Dec;57(1):2453089. doi: 10.1080/07853890.2025.2453089. Epub 2025 Jan 22.


DOI:10.1080/07853890.2025.2453089
PMID:39840609
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11755745/
Abstract

OBJECTIVES: The incidence rate of intervertebral disc degeneration (IVDD) is increasing year by year, which brings great harm to our health. The change of biomechanical factors is an important reason for IVDD. Therefore, more and more studies use finite element (FE) models to analyze the biomechanics of spine. METHODS: In this review, literatures which reported the FE model of intervertebral disc (IVD) were reviewed. We summarized the types and constructional methods of the FE models and analyzed the applications of some representative FE models. RESULTS: The most widely used model was the nonlinear model which considers the behavior of porous elastic materials. As more advanced methods, More and more models which involve penetration parameters were used to simulate the biological behavior and biomechanical properties of IVD. CONCLUSIONS: Personalized modeling should be carried out in order to better provide accurate basis for the diagnosis and treatment of the disease. In addition, microstructure, cell behavior and complex load should be considered in the process of model construction to build a more realistic model.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/507c/11755745/8c2c2d33c8c1/IANN_A_2453089_F0004_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/507c/11755745/15a52f9a675a/IANN_A_2453089_F0001_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/507c/11755745/a3af48a3e26f/IANN_A_2453089_F0002_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/507c/11755745/75bb31d6aaee/IANN_A_2453089_F0003_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/507c/11755745/8c2c2d33c8c1/IANN_A_2453089_F0004_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/507c/11755745/15a52f9a675a/IANN_A_2453089_F0001_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/507c/11755745/a3af48a3e26f/IANN_A_2453089_F0002_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/507c/11755745/75bb31d6aaee/IANN_A_2453089_F0003_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/507c/11755745/8c2c2d33c8c1/IANN_A_2453089_F0004_C.jpg

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Finite element models of intervertebral disc: recent advances and prospects.

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引用本文的文献

[1]
Optimisation of Intervertebral Disc Mechanical Properties and the Impact of Vertebral Alignment in Subject-Specific Finite Element Models.

Int J Numer Method Biomed Eng. 2025-6

本文引用的文献

[1]
Unveiling interactions between intervertebral disc morphologies and mechanical behavior through personalized finite element modeling.

Front Bioeng Biotechnol. 2024-6-10

[2]
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Comput Methods Programs Biomed. 2023-10

[3]
A novel approach for tetrahedral-element-based finite element simulations of anisotropic hyperelastic intervertebral disc behavior.

Front Bioeng Biotechnol. 2022-12-13

[4]
Comparison of two internal fixation systems in lumbar spondylolysis by finite element methods.

Comput Methods Programs Biomed. 2022-5

[5]
Computational Modeling Intervertebral Disc Pathophysiology: A Review.

Front Physiol. 2022-1-13

[6]
A statistical lumbar spine geometry model accounting for variations by Age, Sex, Stature, and body mass index.

J Biomech. 2022-1

[7]
Review of in vitro mechanical testing for intervertebral disc injectable biomaterials.

J Mech Behav Biomed Mater. 2021-11

[8]
Sensitivity of Intervertebral Disc Finite Element Models to Internal Geometric and Non-geometric Parameters.

Front Bioeng Biotechnol. 2021-6-17

[9]
The Role of Panx3 in Age-Associated and Injury-Induced Intervertebral Disc Degeneration.

Int J Mol Sci. 2021-1-22

[10]
Accurate simulation of the herniated cervical intervertebral disc using controllable expansion: a finite element study.

Comput Methods Biomech Biomed Engin. 2021-6

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