Kanan Sofian, Samara Fatin, Dronjak Lara, Mahasneh Amjad, Moyet Matthew, Obeideen Khaled, Gopal Venkatesh
Department of Biology, Chemistry and Environmental Sciences, American University of Sharjah, P.O. Box 26666, Sharjah, United Arab Emirates; Energy Water and Sustainable Environments Research Center (EWSERC), American University of Sharjah, P.O. Box 26666, Sharjah, United Arab Emirates.
Department of Biology, Chemistry and Environmental Sciences, American University of Sharjah, P.O. Box 26666, Sharjah, United Arab Emirates.
Chemosphere. 2025 Mar;372:144120. doi: 10.1016/j.chemosphere.2025.144120. Epub 2025 Jan 21.
Dioxins and analogous derivatives pose significant concerns due to their impact on human health through both acute and prolonged exposures. They have the potential to resist natural degradation processes; therefore, they tend to accumulate in water, sediments, fish, meat, and human adipose tissue. As a result, concerns to both environmental and human health arise among the scientific community and environmental health organizers. Herein, we provide a comprehensive review highlighting recent findings of dioxin and furan pollution with a focus on major environmental and health aspects associated with the exposure to dioxin and its derivatives by assessing the routes of exposure, toxicity, and modes of action. Moreover, VOSviewer was used to understand the research interest within the scientific community in the study of dioxins and furans. Various strategies like remediation, methods of extraction and analysis, as well as protocols required to improve compound filtration and mineralization to enhance the efficiency of environmental cleanup processes.