Young April M, Jahangir Tasfia, Belton Imani, Freeman Edward, Livingston Melvin D
University of Kentucky Center on Drug and Alcohol Research, 845 Angliana Avenue, Lexington KY 40508, United States; University of Kentucky College of Public Health, 111 Washington Avenue, Lexington, KY 40536, United States.
Emory University Rollins School of Public Health, 1518 Clifton Road, Atlanta, GA 30322, United States.
Int J Drug Policy. 2025 Mar;137:104709. doi: 10.1016/j.drugpo.2025.104709. Epub 2025 Jan 21.
Harm reduction vending machines (HRVMs) that dispense safe injection equipment and other supplies have operated globally for more than 30 years, yet few operate in the U.S., particularly in the rural epicenters of drug-related harms. This study explores likelihood of using HRVMs and correlates thereto among people who inject drugs in rural Appalachian Kentucky.
Respondent-driven sampling and outreach were used to recruit participants who were age 18 or older, resided in an Appalachian Kentucky county, and had used opioids and/or injected drugs to get high in the past 30 days. Interviewer-administered questionnaires elicited data on behavioral and demographic characteristics and likelihood of using HRVMs. Analyses were restricted to participants who injected in the past 6 months (n = 259). Generalized estimating equations were used to estimate adjusted prevalence ratios (APRs) for correlates to likelihood of using HRVMs, controlling for lifetime use of brick-and-mortar syringe service programs.
Overall, 57 % reported being likely to use HRVMs. Participants who lacked consistent access to transportation, engaged in receptive and distributive syringe sharing, experienced more lifetime overdoses, and had unsuccessfully attempted to access medications for opioid use disorder (MOUD) reported being more likely to use HRVMs. Heroin and prescription opioid use were negatively associated with likelihood of HRVM use, as was experience of shame around drug use.
Most people who inject drugs in this rural Appalachian sample were likely to use HRVMs, with interest being highest among those at highest risk for injection-related infections and overdose and who had faced difficulty accessing MOUD.
发放安全注射设备及其他用品的减少伤害自动售货机(HRVMs)已在全球运行30多年,但在美国运行的较少,尤其是在与毒品相关危害的农村中心地区。本研究探讨了肯塔基州阿巴拉契亚农村地区注射毒品者使用HRVMs的可能性及其相关因素。
采用应答者驱动抽样和外展方法招募年龄在18岁及以上、居住在肯塔基州阿巴拉契亚县且在过去30天内使用过阿片类药物和/或注射毒品以寻求快感的参与者。由访谈员管理的问卷收集了关于行为和人口统计学特征以及使用HRVMs可能性的数据。分析仅限于过去6个月内有注射行为的参与者(n = 259)。使用广义估计方程来估计与使用HRVMs可能性相关因素经调整的患病率比(APRs),并控制实体注射器服务项目的终身使用情况。
总体而言,57%的人报告有可能使用HRVMs。缺乏稳定交通出行、参与接受性和分配性注射器共享、有更多终身过量用药经历以及获取阿片类药物使用障碍(MOUD)药物尝试失败的参与者报告更有可能使用HRVMs。海洛因和处方阿片类药物的使用与使用HRVMs的可能性呈负相关,吸毒时的羞耻感也是如此。
在这个阿巴拉契亚农村样本中,大多数注射毒品者可能会使用HRVMs,在与注射相关感染和过量用药风险最高且获取MOUD面临困难的人群中兴趣最高。