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Promotion or inhibition? This is a question in gene editing.

作者信息

Tsai Li-Kuang, Han Renzhi, Yang Dongshan, Chen Y Eugene, Zhang Jifeng, Xu Jie

机构信息

Center for Advanced Models Translational Sciences and Therapeutics, University of Michigan Medical School, 2800 Plymouth Road, Ann Arbor, MI 48109, USA.

Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

出版信息

Mol Ther. 2025 Feb 5;33(2):444-446. doi: 10.1016/j.ymthe.2025.01.014. Epub 2025 Jan 21.

Abstract
摘要

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本文引用的文献

3
Enhancement of Precise Gene Editing by the Association of Cas9 With Homologous Recombination Factors.
Front Genet. 2019 Apr 30;10:365. doi: 10.3389/fgene.2019.00365. eCollection 2019.
4
Ectopic expression of RAD52 and dn53BP1 improves homology-directed repair during CRISPR-Cas9 genome editing.
Nat Biomed Eng. 2017 Nov;1(11):878-888. doi: 10.1038/s41551-017-0145-2. Epub 2017 Oct 9.
7
CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair.
Nat Commun. 2018 Mar 19;9(1):1133. doi: 10.1038/s41467-018-03475-7.
9
RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency.
Nat Commun. 2016 Jan 28;7:10548. doi: 10.1038/ncomms10548.
10
Endogenous DNA double-strand breaks: production, fidelity of repair, and induction of cancer.
Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12871-6. doi: 10.1073/pnas.2135498100. Epub 2003 Oct 17.

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