Zakharova N B, Luk'ianov V F
Vopr Med Khim. 1985 Jan-Feb;31(1):111-4.
Alterations in the patterns of hemoglycolysis (ATP, 2,3-diphosphoglycerate, glucose, lactate, pyruvate) were studied after incubation of erythrocytes from 98 patients with chronic ischemic heart disease and 27 practically healthy persons. The incubation of erythrocytes within 2 hrs enabled to detect the typical impairments in regulation of glycolysis occurring in erythrocytes of the patients as well as to find two main types of its alteration, corresponding to clinical manifestations in the circulation insufficiency.
对98例慢性缺血性心脏病患者和27名实际健康者的红细胞进行孵育后,研究了血液糖酵解模式(ATP、2,3 - 二磷酸甘油酸、葡萄糖、乳酸、丙酮酸)的变化。红细胞孵育2小时能够检测到患者红细胞中发生的典型糖酵解调节障碍,以及发现其两种主要变化类型,这与循环功能不全的临床表现相对应。