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奥地利是否应增加食盐加碘量?

[Should the iodination of table salt be increased in Austria?].

作者信息

Galvan G

出版信息

Wien Med Wochenschr. 1985 Feb 15;135(3):71-5.

PMID:3984354
Abstract

Since the main reason of endemic goiter is the avoidable iodine deficiency, this in an unnecessary disease. In Austria an exemplary iodized salt prophylaxis was introduced in 1963. Thanks to this iodized salt prophylaxis endemic cretinism has died out. The incidence of hypothyroidism in newborns is currently 1 : 4600, goiter frequency in the first school year now only 1.1 to 1.5%. In contrast the goiter incidence in girls in the twelfth school year increases to 13.4% and up to one third of adults are afflicted by goiter. Studies of iodine excretion in Feldkirch, Innsbruck, Salzburg, Graz and Vienna on a total of 2627 patients showed an iodine excretion of less than 100 micrograms J/g creatinine in the majority of the patients. This proves that there is still an inadequate iodine supplement. The Austrian Nuclear Medicine Society therefore recommends an increase in the potassium iodide content from the present 10 mg potassium iodide/kg to 20 mg potassium iodide/kg table salt, in keeping with the procedure introduced in Switzerland in 1980. Through this measure a decrease in the goiter frequency to less than 3% is to be expected over a longer period. This will result in a considerable reduction in the costs of diagnosis and therapy for this disease. There might be a temporary increase in hyperthyroidism for a certain period as a result of the increase of the content of iodide in the table salt.

摘要

由于地方性甲状腺肿的主要原因是可避免的碘缺乏,所以这是一种不必要的疾病。1963年奥地利采用了堪称典范的碘盐预防措施。多亏了这种碘盐预防措施,地方性克汀病已绝迹。目前新生儿甲状腺功能减退症的发病率为1:4600,在小学一年级时甲状腺肿的发病率仅为1.1%至1.5%。相比之下,在中学十二年级女生中甲状腺肿发病率增至13.4%,且多达三分之一的成年人患有甲状腺肿。在费尔德基希、因斯布鲁克、萨尔茨堡、格拉茨和维也纳对总共2627名患者进行的碘排泄研究表明,大多数患者的碘排泄量低于100微克碘/克肌酐。这证明碘补充仍然不足。因此,奥地利核医学协会建议按照瑞士1980年采用的做法,将碘化钾含量从目前的每千克食盐含10毫克碘化钾提高到每千克食盐含20毫克碘化钾。通过这一措施,预计甲状腺肿发病率在较长时期内会降至3%以下。这将大大降低这种疾病的诊断和治疗成本。由于食盐中碘含量增加,在一定时期内甲状腺功能亢进症可能会暂时增加。

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