Kleint V
Z Gesamte Inn Med. 1985 Jan 1;40(1):12-7.
The variation of the pulse rate under deep breathing was tested for its suitability in getting informations on the intactness of the autonomous regulation of the heart rate in dialysis patients and those with chronic renal insufficiency. 26 dialysis patients and 17 patients with chronic renal insufficiency with a serum creatinine over 500 mumol/l were examined in comparison to 28 healthy control persons and a group of 10 long-term diabetics, in whom a distinct lesion of the autonomous nervous system could be assumed. Statistically ascertained in the long-term diabetics as well as in the dialysis patients and patients with renal insufficiency a distinct decrease of the frequency modulation could be shown which renders possible a clear separation of the groups. The correlation of the modulation of the frequency to age is unequivocally to be proved only in control persons. It becomes obliterated by the conditions of the disease. The clear lesions in the autonomous regulation of the heart in the groups of patients examined are significant for a number of clinical phenomena and allow conclusion to the necessary regimen of treatment.
测试了深呼吸时脉搏率的变化，以评估其是否适用于获取透析患者和慢性肾功能不全患者心率自主调节完整性的信息。与28名健康对照者和一组10名长期糖尿病患者（假定其自主神经系统有明显病变）相比，对26名透析患者和17名血清肌酐超过500μmol/l的慢性肾功能不全患者进行了检查。经统计确定，长期糖尿病患者以及透析患者和肾功能不全患者的频率调制明显降低，这使得能够清晰地区分这些组。频率调制与年龄的相关性仅在对照者中得到明确证实。疾病状况会使其消失。在所检查的患者组中，心脏自主调节的明显病变对许多临床现象具有重要意义，并有助于得出必要的治疗方案。
