Terwisscha van Scheltinga Sheila, Schoot Reineke A, Routh Jonathan C, Seitz Guido, Kao Simon C, de Keizer Bart, Shulkin Barry, Ewijk Roelof van, McCarville Beth, Casey Dana, Allen-Rhoades Wendy, Mercolini Federico, Merks Hans, Orbach Daniel, Kapadia Tejas, Walterhouse David O, Davila Fajardo Raquel, Hiemcke-Jiwa Laura, Franzius Christiane, De Corti Federica, Tang Vivian, Metts Jonathan, Oberoi Saphna, Vokuhl Christian, Dasgupta Roshni, Birz Suzi, Rodeberg David
Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Department of Urology, Duke University School of Medicine, Durham, North Carolina, USA.
Pediatr Blood Cancer. 2025 Apr;72(4):e31538. doi: 10.1002/pbc.31538. Epub 2025 Jan 23.
Accurate staging of nodal involvement in pediatric sarcoma patients is important to determine correct systemic and local therapy, with the goal to reduce subsequent recurrences. However, differences in lymph node staging strategies, definitions, and treatment protocols between the Children's Oncology Group (COG), European paediatric Soft tissue sarcoma Study Group (EpSSG), and the Cooperative Weichteilsarkom Studiengruppe (CWS) complicate comparisons. In this article, we aim to establish internationally recognized recommendations for lymph node assessment and treatment of children and adolescents diagnosed with rhabdomyosarcoma (RMS) and non-rhabdomyosarcoma soft tissue sarcoma (NRSTS) according to the Consensus Conference Standard Operating Procedure methodology.
准确分期小儿肉瘤患者的淋巴结受累情况对于确定正确的全身和局部治疗至关重要，目的是减少后续复发。然而，儿童肿瘤学组（COG）、欧洲小儿软组织肉瘤研究组（EpSSG）和软组织肉瘤合作研究组（CWS）在淋巴结分期策略、定义和治疗方案上的差异使比较变得复杂。在本文中，我们旨在根据共识会议标准操作程序方法，为诊断为横纹肌肉瘤（RMS）和非横纹肌肉瘤软组织肉瘤（NRSTS）的儿童和青少年的淋巴结评估和治疗制定国际认可的建议。
