[单胺能系统在猫脑乙酰胆碱能结构刺激效应发展中的作用]

[Role of monoaminergic systems in the development of the effect of stimulation of acetylcholinergic brain structures in the cat].

作者信息

Shugalev N P

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1985 Jan-Feb;35(1):103-9.

Abstract

The influence of systemic injection of anticholinesterase substance physostigmine on the behaviour of cats was studied under the conditions of pharmacological stimulation of monoaminergic cerebral systems. Development of the effect of the substance with an increase of its dose was accompanied by a successive alternation of three phases each representing an independent form of behaviour. Each form of behaviour originating in the process of acetylcholinergic stimulation increase was supposed to be caused by an involvement of corresponding monoaminergic system: serotonindopamine-, or noradrenergic one.

摘要

在对单胺能脑系统进行药理刺激的条件下，研究了全身注射抗胆碱酯酶物质毒扁豆碱对猫行为的影响。随着该物质剂量增加，其效应的发展伴随着三个阶段的相继交替，每个阶段代表一种独立的行为形式。假定在乙酰胆碱能刺激增加过程中产生的每种行为形式都是由相应的单胺能系统参与引起的：血清素 - 多巴胺或去甲肾上腺素能系统。

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