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[大鼠内侧丘脑神经元在以下状态下的化学活性特性:氨基甲酸乙酯麻醉、清醒和制动应激]

[Chemoreactive properties of medial thalamic neurons of the rat in the following states: urethane anesthesia, wakefulness and immobilization stress].

作者信息

Kiiatkin E A

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1985 Jan-Feb;35(1):146-54.

PMID:3984501
Abstract

An analysis was carried out by means of microelectrode records and microionophoresis of medial thalamus neurones chemical sensitivity to acetylcholine and noradrenaline in rats under urethane anaesthesia, in free behaviour and in immobilization stress. Significant differences were observed in stability of cellular responses to repeated application of mediators under these conditions and in the correlation of the cells with qualitatively different reactions to these mediators. Along with the functional state of the animals, probability and direction of "spontaneous" changes of neuronal chemoreactive properties significantly depended on the type of sensibility inherent in them at that moment.

摘要

采用微电极记录和微离子电泳方法,对在氨基甲酸乙酯麻醉、自由行为和固定应激状态下的大鼠内侧丘脑神经元对乙酰胆碱和去甲肾上腺素的化学敏感性进行了分析。在这些条件下,观察到细胞对介质重复应用的反应稳定性以及细胞对这些介质不同性质反应的相关性存在显著差异。除了动物的功能状态外,神经元化学活性特性“自发”变化的概率和方向还显著取决于当时它们所固有的敏感性类型。

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