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小肠梗阻的管理及造影剂的治疗作用:一项多中心研究。

Management of small bowel obstruction and therapeutic role of contrast media: A multicenter study.

作者信息

Jaanimäe Liis, Lepner Urmas, Kirsimägi Ülle, Nikkolo Ceith

机构信息

Tartu University Hospital, Surgery Clinic, Puusepa 8, Tartu 51014, Estonia.

University of Tartu, Faculty of Medicine, Tartu 51014, Ravila 19, Tartu 50411, Estonia.

出版信息

Surg Pract Sci. 2022 Dec 15;12:100149. doi: 10.1016/j.sipas.2022.100149. eCollection 2023 Mar.

Abstract

BACKGROUND

Adhesive small bowel obstruction (SBO) accounts for 55-75% of mechanical small bowel obstructions [1,2]. According to guidelines, water-soluble contrast media (CM) is suggested in the diagnostic work-up of adhesive SBO [3], [4], [5]. However, there is currently no consensus on the therapeutic role of water-soluble CM in adhesive SBO [6] or a generally approved protocol as to when CM should be administered, how often should radiographs be taken and how long conservative management can safely be pursued.

MATERIAL AND METHODS

The data of patients who were hospitalized for SBO in two regional hospitals of Estonia between January 2015 and December 2019 were retrospectively collected from the hospitals' electronic databases.

RESULTS

Of 1,008 patients with mechanical SBO included in analysis, 140 (13.9%) were operated on immediately. In the case of conservative management, 575 (66.2%) patients received CM. Resolution occurred in 75.8% of the patients who received CM and in 68.9% of the patients who did not ( = 0.037). Resolution rate was the highest (78.8%) in the group that received CM within 12 h of admission. The duration of symptoms was longer in patients who needed surgical intervention compared to conservatively treated patients (31 h 15 h, <0.001). For patients with a history of a single previous abdominal/pelvic operation, the likelihood of surgical intervention was higher compared to patients whom resolution was achieved with conservative measures (50.9% 38.5%). In patients with three or more previous operations SBO resolved more often with conservative treatment compared to patients who required surgical intervention (22.7% 11.4%; <0.001).

CONCLUSION

The significantly higher rate of SBO resolution in the CM group suggests that CM may have a therapeutic role in SBO treatment, especially when it is administered within 12 h of admission. Patients with longer duration of symptoms and a history of one previous abdominal surgery need more likely surgical treatment.

摘要

背景

粘连性小肠梗阻(SBO)占机械性小肠梗阻的55%-75%[1,2]。根据指南,水溶性造影剂(CM)被推荐用于粘连性SBO的诊断检查[3,4,5]。然而,目前关于水溶性CM在粘连性SBO中的治疗作用尚无共识[6],对于何时应给予CM、应多久拍摄一次X线片以及保守治疗可以安全进行多长时间也没有普遍认可的方案。

材料与方法

回顾性收集2015年1月至2019年12月在爱沙尼亚两家地区医院因SBO住院患者的数据,这些数据来自医院的电子数据库。

结果

纳入分析的1008例机械性SBO患者中,140例(13.9%)立即接受了手术。在保守治疗的情况下,575例(66.2%)患者接受了CM。接受CM的患者中75.8%病情缓解,未接受CM的患者中68.9%病情缓解(P = 0.037)。入院后12小时内接受CM的组缓解率最高(78.8%)。与保守治疗的患者相比,需要手术干预的患者症状持续时间更长(31小时对15小时,P<0.001)。与通过保守措施病情缓解的患者相比,有过一次腹部/盆腔手术史的患者手术干预的可能性更高(50.9%对38.5%)。与需要手术干预的患者相比,有三次或更多次既往手术史的患者SBO通过保守治疗缓解的情况更常见(22.7%对11.4%;P<0.001)。

结论

CM组SBO缓解率显著更高,这表明CM可能在SBO治疗中具有治疗作用,尤其是在入院后12小时内给予时。症状持续时间较长且有过一次腹部手术史的患者更有可能需要手术治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/483d/11749962/0c3a309f9734/gr1.jpg

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