Priya S, Pushpa V H, Avarebeel S, Kalabharathi H L, Jayanthi M K, Doddawad V G
JSS Dental College and Hospital, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India.
Acta Endocrinol (Buchar). 2024 Apr-Jun;20(2):249-255. doi: 10.4183/aeb.2024.249. Epub 2025 Jan 18.
Diabetes mellitus, a chronic metabolic disorder stemming from pancreatic dysfunction, is surging in India, notably among those aged 60 and above. The escalating disease prevalence in this demographic necessitates heightened medication use, escalating the risk of Adverse Drug Reactions (ADRs). This underscores the vital role of ADR monitoring to curtail potential harm.
A 12-month cross-sectional, prospective, observational study engaged 200 participants from the geriatric Outpatient Department (OPD). Diabetic patients in the geriatric OPD, willing to participate, underwent face-to-face evaluations using a structured questionnaire focused on adverse reactions to anti-diabetic medications. The study also included a Knowledge, Attitude, and Practice (KAP) assessment.
Of the 200 patients, 57% were male, 43% female. Thirteen participants (7 male, 6 female) reported ADR encounters during therapy, predominantly categorized as mild in causality and severity. KAP assessments unveiled a robust understanding of ADRs, primarily shaped by physicians and reinforced by pharmacists. Anticipation of ADR occurrence was noted in 70% of respondents, linked to non-compliance and lifestyle factors.
Educating caregivers about the critical importance of monitoring medication adherence among the elderly is imperative. Cultivating an attitude of reporting even minor ADRs to appropriate authorities is essential for harm prevention.
糖尿病是一种源于胰腺功能障碍的慢性代谢紊乱疾病，在印度呈激增态势，在60岁及以上人群中尤为明显。这一人群中疾病患病率不断上升，使得药物使用量增加，进而增加了药物不良反应（ADR）的风险。这凸显了ADR监测在减少潜在危害方面的关键作用。
一项为期12个月的横断面、前瞻性观察性研究纳入了老年门诊部（OPD）的200名参与者。老年OPD中愿意参与的糖尿病患者接受了面对面评估，使用一份侧重于抗糖尿病药物不良反应的结构化问卷。该研究还包括知识、态度和实践（KAP）评估。
200名患者中，57%为男性，43%为女性。13名参与者（7名男性，6名女性）在治疗期间报告了ADR经历，主要在因果关系和严重程度上归类为轻度。KAP评估显示对ADR有较强的理解，主要由医生塑造并由药剂师强化。70%的受访者提到了对ADR发生的预期，与不依从和生活方式因素有关。
必须让护理人员了解监测老年人用药依从性的至关重要性。培养向适当当局报告哪怕是轻微ADR的态度对于预防危害至关重要。
