癌症患者口腔健康问题与营养状况之间的关联：一项使用微型营养评定简表的研究

Association Between Oral Health Complaints and Nutritional Status among Patients with Cancer: A Study Utilising the Mini Nutritional Assessment Short Form.

作者信息

Naik Sachin, Vellappally Sajith, Alateek Mohammed, Al Kheraif Abdulaziz Abdullah, Alghamdi Mohammed, Anil Sukumaran

出版信息

Oral Health Prev Dent. 2025 Jan 23;23:83-91. doi: 10.3290/j.ohpd.c_1827.

DOI:10.3290/j.ohpd.c_1827

PMID:39846970

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11881756/

Abstract

PURPOSE

Oral health problems in patients with cancer can substantially affect their quality of life, treatment outcomes, and overall nutritional well-being. This study investigated the relationship between nutritional status and self-reported oral health complaints in patients with cancer.

MATERIALS AND METHODS

A cross-sectional study was conducted among patients with cancer at the King Saud University Medical City Oncology Center in Riyadh, Saudi Arabia. Patients' nutritional status was assessed using the mini nutritional assessment short form (MNA-SF), and self-reported oral health problems were documented. Data were analysed using the Chi-square test and multinomial logistic regression.

RESULTS

This study included 200 participants who completed both the MNA-SF assessment and self-reported their oral health complaints. Common oral health problems included xerostomia (81%), bleeding gums (60.5%), toothaches (35%), and mouth ulcers (24%). Malnourished individuals reported higher rates of all oral complaints, with 54% of them experiencing bleeding gums, 50% reporting toothaches, and 54% experiencing speech problems. Notably, 71% of malnourished patients reported mouth ulcers (P 0.05). Regression analysis revealed a statistically significant association (P 0.05) between xerostomia and the 'At risk of malnutrition' group, with an odds ratio of 1.004 (95% confidence interval [CI]: 0.411-2.449). In the 'Malnourished' category, mouth ulcers showed a statistically significant association (P 0.05) with an odds ratio of 1.402 (95% CI: 0.409-4.800).

CONCLUSION

Our findings highlighted statistically significant correlations between nutritional status, as assessed using the MNA-SF, and oral health complaints in patients with cancer. Well-nourished individuals reported fewer oral complaints, whereas malnourished patients reported a higher prevalence of oral health issues.

摘要

目的

癌症患者的口腔健康问题会严重影响他们的生活质量、治疗效果及整体营养状况。本研究调查了癌症患者营养状况与自我报告的口腔健康问题之间的关系。

材料与方法

在沙特阿拉伯利雅得国王沙特大学医学城肿瘤中心对癌症患者进行了一项横断面研究。采用微型营养评定简表（MNA-SF）评估患者的营养状况，并记录自我报告的口腔健康问题。使用卡方检验和多项逻辑回归分析数据。

结果

本研究纳入了200名完成MNA-SF评估并自我报告口腔健康问题的参与者。常见的口腔健康问题包括口干（81%）、牙龈出血（60.5%）、牙痛（35%）和口腔溃疡（24%）。营养不良的个体报告的所有口腔问题发生率更高，其中54%的人牙龈出血，50%的人牙痛，54%的人有言语问题。值得注意的是，71%的营养不良患者报告有口腔溃疡（P<0.05）。回归分析显示，口干与“营养不良风险”组之间存在统计学显著关联（P<0.05），比值比为1.004（95%置信区间[CI]：0.411-2.449）。在“营养不良”类别中，口腔溃疡显示出统计学显著关联（P<0.05），比值比为1.402（95%CI：0.409-4.800）。