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盆腔侧方淋巴结清扫术(LPLND)在直肠癌治疗中的应用:印度的当前实践及不断发展的方法

Lateral pelvic lymph node dissection (LPLND) in the treatment of rectal cancer: current practice and evolving approaches in India.

作者信息

Sharma Ankit, Manohkaran Subhathira, Saklani Avanish

机构信息

Colorectal Division, Department of Surgical Oncology, Tata Memorial Hospital, Mumbai, India.

出版信息

Tech Coloproctol. 2025 Jan 23;29(1):55. doi: 10.1007/s10151-024-03081-4.

DOI:10.1007/s10151-024-03081-4
PMID:39847153
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11759476/
Abstract

BACKGROUND

The introduction of total mesorectal excision improved locoregional control for rectal adenocarcinoma significantly. Standardisation of the technique of LPLND is lacking in literature.

METHODS

We describe the current practices of case selection and technical details of lateral lymph node dissection in rectal cancer. We also describe the approach when post neo-adjuvant fibrosis renders standard resection unsafe.

RESULTS

Careful case selection and standardisation of the lateral lymph node dissection technique is important to ensure an oncologically sound and surgically procedure . Step-by-step procedures of LPLND are described in this article, and a video is demonstrated.

CONCLUSIONS

Standardisation of the techniques of lateral lymph node dissection is essential. The procedure has a definite learning curve, requiring considerable expertise to avoid complications and achieve optimal outcomes.

摘要

背景

全直肠系膜切除术的引入显著改善了直肠腺癌的局部区域控制。文献中缺乏侧方淋巴结清扫术(LPLND)技术的标准化。

方法

我们描述了直肠癌病例选择的当前实践以及侧方淋巴结清扫的技术细节。我们还描述了新辅助治疗后纤维化使标准切除不安全时的处理方法。

结果

仔细的病例选择和侧方淋巴结清扫技术的标准化对于确保肿瘤学上合理且手术可行的操作很重要。本文描述了LPLND的逐步操作步骤,并展示了一段视频。

结论

侧方淋巴结清扫技术的标准化至关重要。该手术有明确的学习曲线,需要相当的专业知识以避免并发症并实现最佳结果。

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Lateral pelvic lymph node dissection (LPLND) in the treatment of rectal cancer: current practice and evolving approaches in India.盆腔侧方淋巴结清扫术(LPLND)在直肠癌治疗中的应用:印度的当前实践及不断发展的方法
Tech Coloproctol. 2025 Jan 23;29(1):55. doi: 10.1007/s10151-024-03081-4.
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[Transanal lateral lymph node dissection surgery for 5 cases of mid-low rectal cancer].5例中低位直肠癌经肛门侧方淋巴结清扫术
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Lateral pelvic lymph nodes dissection of rectal neuroendocrine neoplasms: A prospective case-series and literature review.直肠神经内分泌肿瘤的侧方盆腔淋巴结清扫术:一项前瞻性病例系列研究及文献复习。
Surgery. 2024 Nov;176(5):1360-1365. doi: 10.1016/j.surg.2024.07.004. Epub 2024 Aug 14.
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The oncologic benefits of lateral lymph node dissection after neoadjuvant therapy - local control or survival?新辅助治疗后行侧方淋巴结清扫的肿瘤学益处——局部控制还是生存获益?
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Feasibility of Laparoscopic Total Mesorectal Excision with Extended Lateral Pelvic Lymph Node Dissection for Advanced Lower Rectal Cancer after Preoperative Chemoradiotherapy.术前放化疗后腹腔镜全直肠系膜切除联合扩大盆腔侧方淋巴结清扫治疗晚期低位直肠癌的可行性
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本文引用的文献

1
The use of indocyanine green for lateral lymph node dissection in rectal cancer: a novel fancy tool in the armamentarium with questionable benefits.吲哚菁绿在直肠癌侧方淋巴结清扫中的应用:一种在现有医疗手段中颇具新奇感但益处存疑的工具。
Tech Coloproctol. 2024 Aug 12;28(1):96. doi: 10.1007/s10151-024-02964-w.
2
The Learning Curve for Robotic Lateral Pelvic Lymph Node Dissection for Rectal Cancer: A View From the West.直肠癌机器人辅助侧方盆腔淋巴结清扫术的学习曲线:来自西方的视角
Dis Colon Rectum. 2024 Oct 1;67(10):1281-1290. doi: 10.1097/DCR.0000000000003424. Epub 2024 Jul 3.
3
Prediction model of the risk for lateral local recurrence in locally advanced rectal cancer without enlarged lateral lymph nodes: Lessons from a Japanese multicenter pooled analysis of 812 patients.无侧方淋巴结肿大的局部进展期直肠癌侧方局部复发风险预测模型:来自日本一项对812例患者的多中心汇总分析的经验教训
Ann Gastroenterol Surg. 2023 Sep 19;8(2):284-292. doi: 10.1002/ags3.12742. eCollection 2024 Mar.
4
Lateral Pelvic Nodal Management and Patterns of Failure in Patients Receiving Short-Course Radiation for Locally Advanced Rectal Cancer.局部晚期直肠癌患者接受短程放疗时的盆腔侧方淋巴结处理及失败模式
Dis Colon Rectum. 2024 Jan 1;67(1):54-61. doi: 10.1097/DCR.0000000000002936. Epub 2023 Sep 25.
5
Management of lateral pelvic lymph nodes in rectal cancer.直肠癌侧方盆腔淋巴结的处理。
J Surg Oncol. 2023 Jun;127(8):1264-1270. doi: 10.1002/jso.27317.
6
A novel technique for laparoscopic abdominoperineal resection with en bloc right pelvic lymph nodal dissection in the case of locally advanced low rectal cancers involving seminal vesicles-a video vignette.一种针对局部晚期低位直肠癌累及精囊的腹腔镜腹会阴联合切除术并整块切除右侧盆腔淋巴结清扫的新技术——视频病例展示
Colorectal Dis. 2023 Jul;25(7):1556-1557. doi: 10.1111/codi.16586. Epub 2023 May 10.
7
Magnetic Resonance Imaging Directed Surgical Decision Making for Lateral Pelvic Lymph Node Dissection in Rectal Cancer After Total Neoadjuvant Therapy (TNT).磁共振成像引导下全新辅助治疗后直肠癌侧方盆腔淋巴结清扫术的外科决策。
Ann Surg. 2022 Oct 1;276(4):654-664. doi: 10.1097/SLA.0000000000005589. Epub 2022 Jul 15.
8
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J Clin Oncol. 2022 Aug 10;40(23):2546-2556. doi: 10.1200/JCO.22.00032. Epub 2022 Apr 28.
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The Role of Simultaneous Integrated Boost in Locally Advanced Rectal Cancer Patients with Positive Lateral Pelvic Lymph Nodes.同步整合加量放疗在伴有阳性盆腔侧方淋巴结的局部晚期直肠癌患者中的作用
Cancers (Basel). 2022 Mar 24;14(7):1643. doi: 10.3390/cancers14071643.
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Combination of extramural venous invasion and lateral lymph node size detected with magnetic resonance imaging is a reliable biomarker for lateral lymph node metastasis in patients with rectal cancer.磁共振成像检测到的腔外静脉侵犯和侧方淋巴结大小是直肠癌患者侧方淋巴结转移的可靠生物标志物。
World J Surg Oncol. 2022 Jan 5;20(1):5. doi: 10.1186/s12957-021-02464-3.