Marx G R, Allen H D, Goldberg S J, Flinn C J
Am J Cardiol. 1985 Apr 15;55(9):1162-7. doi: 10.1016/0002-9149(85)90656-3.
Right atrial velocities measured perpendicular to the atrial septum by Doppler echocardiography in patients with atrial septal defects (ASD) have a discernible morphology that may bear a relation to shunt magnitude. The integral of the right atrial Doppler waveform was compared with shunt magnitude measured at cardiac catheterization or nuclear shunt scan in 17 ASD patients. For control subjects, the mean right atrial velocity was 15 +/- 4 cm/s (+/- standard deviation) and that for ASD patients was 41 +/- 11 cm/s (p less than 0.001). Doppler pulmonary-to-systemic flow ratio (Qp:Qs) correlated with catheterization Qp:Qs ratio (n = 9, r = 0.85, SEE = 0.27) and with nuclear Qp:Qs ratios (n = 8, r = 0.60, SEE = 0.51). Mean transatrial septal velocity in ASD patients correlated with catheterization Qp:Qs ratio (n = 9, r = 0.8, SEE = 6.0) and with simultaneous Doppler Qp:Qs ratio (n = 16, r = 0.89, SEE = 4.9, y = 16.2 +/- 8.3). Although Qp:Qs ratio can be approximated by measuring pulmonary and systemic flow by Doppler echocardiography in many ASD patients, this newly described method allows estimation of Qp:Qs ratio. It is useful when these more conventional measurements cannot be performed because of turbulence or when inadequate imaging prevents Doppler pulmonary to systemic flow measurement.
通过多普勒超声心动图测量房间隔缺损（ASD）患者垂直于房间隔的右心房速度，其形态具有可辨性，可能与分流大小有关。对17例ASD患者的右心房多普勒波形积分与心导管检查或核素分流扫描测得的分流大小进行了比较。对照组的平均右心房速度为15±4cm/s（±标准差），ASD患者为41±11cm/s（p<0.001）。多普勒肺循环与体循环血流量比值（Qp:Qs）与心导管检查Qp:Qs比值相关（n=9，r=0.85，标准误=0.27），与核素Qp:Qs比值相关（n=8，r=0.60，标准误=0.51）。ASD患者的平均跨房间隔速度与心导管检查Qp:Qs比值相关（n=9，r=0.8，标准误=6.0），与同时测得的多普勒Qp:Qs比值相关（n=16，r=0.89，标准误=4.9，y=16.2±8.3）。虽然在许多ASD患者中，通过多普勒超声心动图测量肺循环和体循环血流量可近似得出Qp:Qs比值，但这种新描述的方法可用于估算Qp:Qs比值。当由于湍流无法进行这些更传统的测量，或成像不足妨碍多普勒测量肺循环到体循环血流量时，该方法很有用。
