Wang Chengran, Feng Yanshuo, Rong Xinao, Yan Jingguo, Lv Baisong, Jiang Hongyu, Duan Lian, Jiang Jinlan
Department of Scientific Research Center, China-Japan Union Hospital of Jilin University, Changchun, 130033, Jilin Province, People's Republic of China.
Department of Intensive Care Unit, Dunhua Hospital, The First Hospital of Jilin University, Dunhua, Jilin Province, People's Republic of China.
Stem Cell Res Ther. 2025 Jan 23;16(1):18. doi: 10.1186/s13287-025-04133-8.
Interest in prostate cancer as a research topic has gradually increased. As a result, a series of innovative treatment strategies have emerged with an in-depth understanding of the disease. Owing to their unique biological characteristics, mesenchymal stromal cell exosomes (MSC-Exos) have garnered significant attention for their potential to deliver targeted drugs and enable precise prostate cancer treatment. Herein, prostate cancer treatment with MSC-Exos drug-delivery systems is reviewed. This review provides a comprehensive introduction to the advantages of these systems, current research trends and progress, as well as an analysis of current challenges and future research directions. Moreover, this review lays a solid foundation for the continued development and application of MSC-Exos.
作为一个研究课题，对前列腺癌的关注已逐渐增加。因此，随着对该疾病的深入了解，一系列创新的治疗策略应运而生。间充质基质细胞外泌体（MSC-Exos）因其独特的生物学特性，在递送靶向药物及实现前列腺癌精准治疗方面的潜力而备受关注。本文对采用MSC-Exos药物递送系统治疗前列腺癌进行综述。本综述全面介绍了这些系统的优势、当前的研究趋势与进展，并分析了当前面临的挑战及未来的研究方向。此外，本综述为MSC-Exos的持续开发与应用奠定了坚实基础。
