Cho Jae Hoon, Suh Jeffrey D, Lim Young Chang
Department of Otorhinolaryngology-Head and Neck Surgery, Konkuk University College of Medicine, Seoul, Korea.
Department of Otolaryngology-Head and Neck Surgery, University of California, Los Angeles, Los Angeles, CA, USA.
Clin Exp Otorhinolaryngol. 2025 May;18(2):180-187. doi: 10.21053/ceo.2024.00346. Epub 2025 Jan 24.
This study aimed to calculate the age-adjusted incidence rate of head and neck cancer (HNC) in South Korea from 1999 to 2020 and to analyze HNC incidence trends while excluding the effects of population aging.
Data were obtained from the Cancer Registration Statistics Program. All 12 types of HNCs were analyzed. Crude incidence rates and the number of new cases from 1999 to 2020 were presented by sex and age group. Age-adjusted incidence rates were calculated using the World Standard Population (World Health Organization [WHO] 2000-2025), and trends were assessed.
Although the crude incidence rates of all HNCs increased steadily from 1999 to 2020, the absolute values remained low in most cases, at less than 2 per 100,000. The male-to-female ratio was 1 or higher for all HNCs except thyroid cancer, and 10 or higher for laryngeal and hypopharyngeal cancers. Age-adjusted incidence trends showed a gradual increase for tongue cancer, tonsil cancer, major salivary gland cancer, and thyroid cancer, a decrease for laryngeal cancer, and no significant change for the remaining HNCs.
Excluding the effects of population aging, tongue cancer, tonsil cancer, major salivary gland cancer, and thyroid cancer have increased in South Korea over the past 20 years, while laryngeal cancer has decreased.
本研究旨在计算1999年至2020年韩国头颈癌（HNC）的年龄调整发病率，并在排除人口老龄化影响的情况下分析HNC发病率趋势。
数据来自癌症登记统计项目。对所有12种头颈癌类型进行了分析。按性别和年龄组列出了1999年至2020年的粗发病率和新发病例数。使用世界标准人口（世界卫生组织[WHO]2000 - 2025年）计算年龄调整发病率，并评估趋势。
尽管从1999年到2020年所有头颈癌的粗发病率稳步上升，但在大多数情况下绝对值仍然较低，每10万人中不到2例。除甲状腺癌外，所有头颈癌的男女比例均为1或更高，喉癌和下咽癌的男女比例为10或更高。年龄调整发病率趋势显示，舌癌、扁桃体癌、大唾液腺癌和甲状腺癌呈逐渐上升趋势，喉癌呈下降趋势，其余头颈癌无显著变化。
在排除人口老龄化影响后，过去20年韩国舌癌、扁桃体癌、大唾液腺癌和甲状腺癌有所增加，而喉癌有所下降。
