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逐步直径血栓切除术支架分析

Analysis of gradual diameter thrombectomy stent .

作者信息

Shen Caifeng, Ma Zhenjian, Li Hong, Wei Ming

机构信息

Clinical College of Neurology, Neurosurgery and Neurorehabilitation, Tianjin Medical University, Tianjin, 300350, China.

Department of Surgery, Ecological City Hospital, Tianjin Fifth Central Hospital, Tianjin, 300451, China.

出版信息

Transl Neurosci. 2025 Jan 18;16(1):20220351. doi: 10.1515/tnsci-2022-0351. eCollection 2025 Jan 1.

DOI:10.1515/tnsci-2022-0351
PMID:39850339
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11751670/
Abstract

OBJECTIVE

To analyze the effect of gradient thrombectomy stent .

METHODS

The cerebrovascular fluid circulation model was made and fixed on the test table. About 0.9% sodium chloride injection was injected to the vascular model through a miniature water pump to circulate it. Four kinds of thrombus products containing different red blood cell (RBC) volumes of 0, 5, 40, and 80% were placed at the target location as thrombus. Each type of thrombus was removed five times using SOLITAIRE stent and gradient thrombectomy stent. The thrombectomy effects were observed by comparison of the two types of stents.

RESULTS

Thrombus containing 80% volume of RBC escaped thrombus fragments during thrombectomy with both stents. Thrombus containing 0% volume of RBC (rich in fibrin) had poor chimerism with stents. In the thrombus containing 0% RBC volume, there was no statistically significant difference between the two stents ( = 1). Thrombus removal was successful in all cases.

CONCLUSION

The gradient thrombectomy stent is as effective as the currently used thrombectomy stent studies, and there is much room for improvement.

摘要

目的

分析梯度取栓支架的效果。

方法

制作脑血管流体循环模型并固定在试验台上。通过微型水泵向血管模型内注入约0.9%的氯化钠注射液使其循环。将含有不同红细胞(RBC)体积分数分别为0%、5%、40%和80%的四种血栓产物置于目标位置作为血栓。每种血栓分别使用SOLITAIRE支架和梯度取栓支架进行五次取栓操作。通过比较两种支架观察取栓效果。

结果

红细胞体积分数为80%的血栓在两种支架取栓过程中均有血栓碎片逃逸。红细胞体积分数为0%(富含纤维蛋白)的血栓与支架的嵌合性较差。在红细胞体积分数为0%的血栓中,两种支架之间无统计学显著差异(=1)。所有病例取栓均成功。

结论

梯度取栓支架与目前使用的取栓支架效果相当 研究,且有很大的改进空间。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa06/11751670/b039e8adf85d/j_tnsci-2022-0351-fig005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa06/11751670/771bd081f991/j_tnsci-2022-0351-fig001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa06/11751670/07ab7a0d67d2/j_tnsci-2022-0351-fig002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa06/11751670/c4b3ea634def/j_tnsci-2022-0351-fig003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa06/11751670/5b6a7fb128aa/j_tnsci-2022-0351-fig004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa06/11751670/b039e8adf85d/j_tnsci-2022-0351-fig005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa06/11751670/771bd081f991/j_tnsci-2022-0351-fig001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa06/11751670/07ab7a0d67d2/j_tnsci-2022-0351-fig002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa06/11751670/c4b3ea634def/j_tnsci-2022-0351-fig003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa06/11751670/5b6a7fb128aa/j_tnsci-2022-0351-fig004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa06/11751670/b039e8adf85d/j_tnsci-2022-0351-fig005.jpg

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Simulation of stent retriever thrombectomy in acute ischemic stroke by finite element analysis.通过有限元分析模拟急性缺血性脑卒中支架取栓术。
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In vitro study for the evaluation of transluminal aspiration as a novel treatment option for thrombosis in the HeartWare HVAD.
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