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种族与原发性开角型青光眼

Race and primary open-angle glaucoma.

作者信息

Martin M J, Sommer A, Gold E B, Diamond E L

出版信息

Am J Ophthalmol. 1985 Apr 15;99(4):383-7. doi: 10.1016/0002-9394(85)90001-7.

Abstract

A comparison of racial distributions for three groups of patients showed that 115 of 140 patients (81.6%) with open-angle glaucoma, 221 of 392 patients (56.4%) with ocular hypertension, and 1,028 of 2,109 patients (48.7%) in a random sample were black. Average age at diagnosis was significantly (P = .006) higher for whites than for blacks (69.1 years vs 63.7 years). Black patients with primary open-angle glaucoma had a significantly larger mean cup-disk ratio (P less than or equal to .002) and a higher but not significantly higher mean intraocular pressure at the time of diagnosis. Advanced glaucomatous visual field loss was more frequent at the time of diagnosis in blacks (43 of 129 patients or 33.3%) than in whites (five of 27 patients or 18.5%), but this difference was not significant.

摘要

对三组患者的种族分布进行比较后发现,开角型青光眼患者中140人中有115人(81.6%)为黑人,高眼压症患者中392人中有221人(56.4%)为黑人,随机样本中2109名患者中有1028人(48.7%)为黑人。白人诊断时的平均年龄显著高于黑人(P = 0.006)(69.1岁对63.7岁)。原发性开角型青光眼的黑人患者诊断时平均杯盘比显著更大(P≤0.002),平均眼压更高但差异不显著。诊断时,黑人患者(129名患者中有43人,即33.3%)比白人患者(27名患者中有5人,即18.5%)发生晚期青光眼性视野缺损更为频繁,但这种差异并不显著。

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