Bensaid Amine, Boukroute Marouane, Bekkaoui Safae, Berrichi Hajar, Elrhalete Abdelilah, Mimouni Hamza, Oujidi Younes, Bkiyar Houssam, Housni Brahim, Mimouni Ahmed
Intensive Care Unit, Mohammed VI University Hospital Center, Faculty of Medicine and Pharmacy, Oujda, Morocco.
Mohammed First University Oujda, Oujda, Morocco.
Radiol Case Rep. 2025 Jan 3;20(3):1658-1661. doi: 10.1016/j.radcr.2024.12.018. eCollection 2025 Mar.
Wernicke's Encephalopathy (WE) is a rare but severe condition primarily caused by thiamine deficiency, often seen in pregnant women who experience severe vomiting, such as in hyperemesis gravidarum. This case report details a 38-year-old woman at 27 weeks of gestation who developed altered consciousness, cerebellar ataxia, and hyperlactatemia following persistent vomiting. Brain MRI demonstrated characteristic bilateral abnormalities consistent with WE. Early recognition and prompt intravenous thiamine administration led to significant clinical improvement. This case emphasizes the importance of maintaining a high level of suspicion and initiating immediate treatment to prevent irreversible neurological damage in pregnant women presenting with severe vomiting and neurological symptoms. A unique feature of this case is the development of Wernicke's encephalopathy secondary to hyperemesis gravidarum, further complicated by severe pre-eclampsia.
韦尼克脑病（WE）是一种罕见但严重的疾病，主要由硫胺素缺乏引起，常见于患有严重呕吐的孕妇，如妊娠剧吐。本病例报告详细介绍了一名38岁、妊娠27周的女性，在持续呕吐后出现意识改变、小脑共济失调和高乳酸血症。脑部磁共振成像（MRI）显示出符合韦尼克脑病的特征性双侧异常。早期识别并及时静脉注射硫胺素使临床症状显著改善。本病例强调了对于出现严重呕吐和神经症状的孕妇，保持高度怀疑并立即开始治疗以预防不可逆神经损伤的重要性。该病例的一个独特之处是继发于妊娠剧吐的韦尼克脑病，且因重度子痫前期而进一步复杂化。
