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Ten years' single surgeon experience of excision and primary anastomosis urethroplasty for traumatic urethral stricture: an analysis of risk factors for urethral stricture recurrence.

作者信息

Satyagraha Paksi, Wibowo Edi, Daryanto Besut, Duarsa Gede Wirya Diptanala Putra, Wijaya Adrianus Gupta, Dhani Fauzan Kurniawan

机构信息

Urology Department, Faculty of Medicine, Universitas Brawijaya, Saiful Anwar General Hospital, Malang.

出版信息

Arch Ital Urol Androl. 2025 Mar 28;97(1):13268. doi: 10.4081/aiua.2025.13268. Epub 2025 Jan 23.

Abstract

INTRODUCTION

Excision and primary anastomosis (EPA) urethroplasty is the standard treatment for traumatic urethral strictures, but managing them remains challenging for urologists. Identifying factors leading to EPA urethroplasty failure benefits both patients and surgeons. This study aims to analyze risk factors for urethral stricture recurrence after one-year follow-up of EPA urethroplasty.

MATERIALS AND METHODS

Data on male patients undergoing EPA urethroplasty at the Urology Department of Saiful Anwar General Hospital from January 2013 until December 2023 were prospectively recorded. Successful urethroplasty, defined as the absence of additional treatment necessity, was assessed until 12 months follow-up. Demographic data, time to surgery, stricture etiology, comorbidities, prior urethral interventions, and operation steps were recorded. Univariate and multivariate Cox regression analyses were performed using IBM SPSS Statistics version 21.

RESULT

Total 95 patients were observed, and 89 patients were included, averaging 41.2 ± 15.59 years old. EPA urethroplasty succeeded in 91% of cases over a median follow-up of 16.3 months. Pelvic fracture urethral injury (PFUI) was the predominant etiology in 74% of cases, with an average stricture length of 25.4 ± 16.3 mm. The average time to surgery was performed on average 6.67 ± 4.07 months after diagnosis. In univariate analysis, body mass index (BMI), time to surgery, and stricture length were associated with urethral stricture recurrence. However, only time to surgery showed a significant association in multivariate analysis.

CONCLUSIONS

Obesity, the length of the stricture, and delayed surgical intervention are associated with an increased risk of urethral stricture recurrence in patients following EPA. EPA urethroplasty demonstrates a high success rate in managing traumatic urethral strictures.

摘要

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