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全肺灌洗患者的快速拔管:一例报告

Fast-Track Extubation in a Patient Undergoing Whole Lung Lavage: A Case Report.

作者信息

Sandeep Gade, Singha Subrata K, Gupta Anil, Chinnadurai Keerthi, Gupta Harishchandra

机构信息

Cardiac Anaesthesiology, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India.

Department of Anaesthesiology, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India.

出版信息

Ann Card Anaesth. 2025 Jan 1;28(1):80-83. doi: 10.4103/aca.aca_163_24. Epub 2025 Jan 24.

DOI:10.4103/aca.aca_163_24
PMID:39851155
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11902368/
Abstract

Pulmonary alveolar proteinosis (PAP) is a rare pulmonary pathology characterized by the accumulation of surfactant within type II alveolar epithelial cells. Whole lung lavage is the standard treatment for pulmonary alveolar proteinosis involving a large volume of fluid is infused into one lung and subsequently retrieved while the other lung is remains ventilated. Fast-tracking a patient undergoing whole lung lavage requires vigilant monitoring of arterial blood gases, fluid status, and respiratory mechanics. We report a case of a patient who underwent whole lung lavage for PAP, where early extubation was performed, avoiding the complications associated with prolonged mechanical ventilation.

摘要

肺泡蛋白沉积症(PAP)是一种罕见的肺部疾病,其特征是表面活性物质在Ⅱ型肺泡上皮细胞内积聚。全肺灌洗是肺泡蛋白沉积症的标准治疗方法,即向一侧肺内注入大量液体,随后在另一侧肺保持通气的情况下将注入的液体回收。对接受全肺灌洗的患者进行快速康复需要密切监测动脉血气、液体状态和呼吸力学。我们报告了一例因肺泡蛋白沉积症接受全肺灌洗的患者,该患者进行了早期拔管,避免了与长时间机械通气相关的并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9ba/11902368/677ec0216b32/ACA-28-80-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9ba/11902368/cfd61d2c3fa1/ACA-28-80-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9ba/11902368/3a07ba4ac67c/ACA-28-80-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9ba/11902368/677ec0216b32/ACA-28-80-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9ba/11902368/cfd61d2c3fa1/ACA-28-80-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9ba/11902368/3a07ba4ac67c/ACA-28-80-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9ba/11902368/677ec0216b32/ACA-28-80-g003.jpg

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本文引用的文献

1
Anesthetic Challenges During Whole Lung Lavage: A Case Report.全肺灌洗术中的麻醉挑战:一例报告。
Cureus. 2023 Jan 11;15(1):e33659. doi: 10.7759/cureus.33659. eCollection 2023 Jan.
2
Update on Diagnosis and Treatment of Adult Pulmonary Alveolar Proteinosis.成人肺泡蛋白沉积症的诊断与治疗进展
Ther Clin Risk Manag. 2021 Aug 10;17:701-710. doi: 10.2147/TCRM.S193884. eCollection 2021.
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Anaesthetic considerations for whole lung lavage for pulmonary alveolar proteinosis.肺泡蛋白沉积症全肺灌洗的麻醉注意事项
Ghana Med J. 2019 Sep;53(3):248-251. doi: 10.4314/gmj.v53i3.9.
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Pulmonary alveolar proteinosis.
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Rev Port Pneumol. 2014 Sep-Oct;20(5):254-9. doi: 10.1016/j.rppneu.2014.04.004. Epub 2014 Jul 18.
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Eur Respir Rev. 2011 Jun;20(120):98-107. doi: 10.1183/09059180.00001311.
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Pulmonary alveolar proteinosis.肺泡蛋白沉积症。
Respir Care. 2011 Jul;56(7):1016-28. doi: 10.4187/respcare.01125. Epub 2011 Apr 15.
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Pulmonary alveolar proteinosis.肺泡蛋白沉积症
N Engl J Med. 2003 Dec 25;349(26):2527-39. doi: 10.1056/NEJMra023226.