Matsuda Naomi, Takamatsu Yasuyuki, Sawada Makoto, Aiba Ikuko
Department of Rehabilitation, NHO Higashinagoya National Hospital, Nagoya 465-8620, Japan.
Department of Rehabilitation Sciences, Graduate School of Life and Health Sciences, Chubu University, Kasugai 487-8501, Japan.
Brain Sci. 2025 Jan 17;15(1):88. doi: 10.3390/brainsci15010088.
: Progressive supranuclear palsy (PSP) is characterized by early postural instability and gait dysfunction, with frequent falls. Rehabilitation is an important therapeutic approach for motor dysfunction in patients with PSP. However, no conclusions have yet been drawn regarding the beneficial effects of rehabilitation in PSP, including the optimal duration of rehabilitation and differences in treatment effects among PSP subtypes. Herein, we investigated the effects of short-term rehabilitation and separately analyzed the effects on patients with PSP-Richardson's syndrome (RS) and PSP-progressive gait freezing (PGF). : The participants underwent several therapeutic exercise programs individualized for each participant, performed over 2 weeks. Analysis was performed on 25 patients with PSP-RS and eight with PSP-PGF. : Short-term rehabilitation improved the Berg Balance Scale score in both the PSP-RS and PSP-PGF groups, step length on the symptom-dominant side in PSP-RS, the coefficient of variation of step length on the symptom-dominant side, and the stance phase of the Symmetry Index in PSP-PGF. : Overall, this 2-week short-term rehabilitation intervention was shown to have beneficial effects on balance in patients with PSP-RS and PSP-PGF.
进行性核上性麻痹（PSP）的特征是早期姿势不稳和步态功能障碍，且经常跌倒。康复是PSP患者运动功能障碍的重要治疗方法。然而，关于康复对PSP的有益效果，包括康复的最佳持续时间以及PSP各亚型之间治疗效果的差异，尚未得出结论。在此，我们研究了短期康复的效果，并分别分析了其对PSP-理查森综合征（RS）患者和PSP-进行性步态冻结（PGF）患者的影响。：参与者接受了针对每个参与者量身定制的多个治疗性锻炼计划，为期2周。对25例PSP-RS患者和8例PSP-PGF患者进行了分析。：短期康复改善了PSP-RS组和PSP-PGF组的伯格平衡量表评分、PSP-RS症状主导侧的步长、症状主导侧步长的变异系数以及PSP-PGF中对称指数的站立期。：总体而言，这一为期2周的短期康复干预对PSP-RS和PSP-PGF患者的平衡有有益影响。
