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揭开无形之谜:拓扑数据分析成为放射学诊断武器库中的新前沿。

Unraveling the Invisible: Topological Data Analysis as the New Frontier in Radiology's Diagnostic Arsenal.

作者信息

Singh Yashbir, Quaia Emilio

机构信息

Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA.

Department of Radiology, University of Padova, 35127 Padova, Italy.

出版信息

Tomography. 2025 Jan 9;11(1):6. doi: 10.3390/tomography11010006.

DOI:10.3390/tomography11010006
PMID:39852686
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11768448/
Abstract

This commentary examines Topological Data Analysis (TDA) in radiology imaging, highlighting its revolutionary potential in medical image interpretation. TDA, which is grounded in mathematical topology, provides novel insights into complex, high-dimensional radiological data through persistent homology and topological features. We explore TDA's applications across medical imaging domains, including tumor characterization, cardiovascular imaging, and COVID-19 detection, where it demonstrates 15-20% improvements over traditional methods. The synergy between TDA and artificial intelligence presents promising opportunities for enhanced diagnostic accuracy. While implementation challenges exist, TDA's ability to uncover hidden patterns positions it as a transformative tool in modern radiology.

摘要

本评论探讨了放射学成像中的拓扑数据分析(TDA),强调了其在医学图像解读方面的变革潜力。TDA基于数学拓扑学,通过持久同调与拓扑特征,为复杂的高维放射学数据提供了全新见解。我们探讨了TDA在医学成像领域的应用,包括肿瘤特征描述、心血管成像以及新冠病毒疾病(COVID-19)检测,在这些领域中,TDA相较于传统方法展现出了15%至20%的提升。TDA与人工智能之间的协同作用为提高诊断准确性带来了广阔机遇。尽管存在实施挑战,但TDA揭示隐藏模式的能力使其成为现代放射学中的变革性工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee30/11768448/e9ba5cbbe8a9/tomography-11-00006-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee30/11768448/e9ba5cbbe8a9/tomography-11-00006-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee30/11768448/e9ba5cbbe8a9/tomography-11-00006-g001.jpg

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本文引用的文献

1
Radiation Dose Optimization in Radiology: A Comprehensive Review of Safeguarding Patients and Preserving Image Fidelity.放射学中的辐射剂量优化:保障患者安全与保持图像保真度的全面综述
Cureus. 2024 May 22;16(5):e60846. doi: 10.7759/cureus.60846. eCollection 2024 May.
2
Advanced Computational Methods for Radiation Dose Optimization in CT.CT 辐射剂量优化的先进计算方法
Diagnostics (Basel). 2024 Apr 29;14(9):921. doi: 10.3390/diagnostics14090921.
3
A novel multi-task machine learning classifier for rare disease patterning using cardiac strain imaging data.
一种利用心脏应变成像数据对罕见疾病进行模式识别的新型多任务机器学习分类器。
Sci Rep. 2024 May 9;14(1):10672. doi: 10.1038/s41598-024-61201-4.
4
Topological data analysis in medical imaging: current state of the art.医学成像中的拓扑数据分析:当前技术现状
Insights Imaging. 2023 Apr 1;14(1):58. doi: 10.1186/s13244-023-01413-w.
5
Topological data analysis in biomedicine: A review.生物医学中的拓扑数据分析:综述。
J Biomed Inform. 2022 Jun;130:104082. doi: 10.1016/j.jbi.2022.104082. Epub 2022 May 1.
6
Network Analysis of Time Series: Novel Approaches to Network Neuroscience.时间序列的网络分析:网络神经科学的新方法。
Front Neurosci. 2022 Feb 11;15:787068. doi: 10.3389/fnins.2021.787068. eCollection 2021.
7
Applications of Topological Data Analysis in Oncology.拓扑数据分析在肿瘤学中的应用。
Front Artif Intell. 2021 Apr 13;4:659037. doi: 10.3389/frai.2021.659037. eCollection 2021.
8
A COVID-19 Drug Repurposing Strategy through Quantitative Homological Similarities Using a Topological Data Analysis-Based Framework.一种基于拓扑数据分析框架,通过定量同源相似性进行COVID-19药物重新利用的策略。
Pharmaceutics. 2021 Apr 2;13(4):488. doi: 10.3390/pharmaceutics13040488.
9
Topological Data Analysis of Coronary Plaques Demonstrates the Natural History of Coronary Atherosclerosis.基于冠状动脉斑块的拓扑数据分析可展示冠状动脉粥样硬化的自然病史。
JACC Cardiovasc Imaging. 2021 Jul;14(7):1410-1421. doi: 10.1016/j.jcmg.2020.11.009. Epub 2021 Jan 13.