Vaccine hesitancy, which refers to the reluctance to be vaccinated, poses a major risk to public health in preventing infectious diseases. This hesitancy has been evident for many years, especially regarding childhood vaccines. The main factors contributing to this hesitancy include religious or personal beliefs, concerns about safety and efficacy, and desire to receive more information from healthcare providers. This literature review examines hesitancy regarding COVID-19 vaccines in different population segments in Turkey. Hesitancy rates and reasons in the general population and specific groups such as pregnant women, parents, healthcare workers and students were presented based on published research articles. Approximately half of the Turkish population declared their hesitancy towards COVID-19 vaccines. A negative correlation was found between vaccine hesitancy and health literacy. The relationship between COVID-19 vaccine hesitancy and religiosity was also investigated. Age is another factor affecting this vaccine hesitancy. Older age was shown to be correlated with positive attitude towards COVID-19 vaccination. Moreover, participants with positive attitudes towards other vaccines, those with chronic diseases and those with a personal history of COVID-19 were more likely to have positive perceptions of COVID-19 vaccines. Higher life satisfaction and non-smoking status were associated with a higher likelihood of COVID-19 vaccine acceptance. Increased scientific data on the efficacy and side effects of COVID-19 vaccines and more information from healthcare professionals would likely reduce the hesitancy towards COVID-19 vaccines.