Department of Public Health, Division of Epidemiology, Faculty of Medicine, Dokuz Eylül University, Izmir, Turkey.
Department of Public Health, Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Epidemiol Infect. 2023 Nov 24;151:e199. doi: 10.1017/S0950268823001875.
This systematic review and meta-analysis aims to estimate the prevalence of coronavirus disease 2019 (COVID-19) vaccine hesitancy in Turkey, which can aid future health policies and strategies. A comprehensive search was conducted on various databases using keywords related to COVID-19 vaccine hesitancy in Turkey. Quality assessment was performed using Joanna Briggs Institute (JBI) checklist for prevalence studies. Data extraction was conducted. The random effect model (DerSimonian and Laird method) was used in pooled prevalence data analysis (95% confidence interval [CI]). A total of 1,072 articles were identified. After removing duplicates and excluding articles, 61 articles remained for bias assessment. Among these, 19 articles with low risk of bias were included in the review and meta-analysis. Total population included in the analysis was 15,164, vaccine hesitancy was 30.5% (95% Cl: 24.3-36.8%). Prevalence of the vaccine hesitancy was found to be 39.8% (95% Cl: 31.4-48.2%) in studies conducted before the initiation of vaccination, while in studies conducted after the commencement of vaccination, hesitancy was 20.4% (95% Cl: 12.9-28%). We suggest conducting high-quality studies in different populations to understand the level of vaccine hesitancy, as many of the previous studies have mainly focused on healthcare workers and students, and rest were community-based studies, which have generally shown high bias. Also, we suggest that early vaccination can reduce vaccine hesitancy.
本系统评价和荟萃分析旨在估计土耳其 2019 年冠状病毒病（COVID-19）疫苗犹豫的流行率，这有助于未来的卫生政策和策略。使用与土耳其 COVID-19 疫苗犹豫相关的关键词，在各种数据库上进行了全面搜索。使用 Joanna Briggs 研究所（JBI）检查表对患病率研究进行了质量评估。进行了数据提取。使用随机效应模型（DerSimonian 和 Laird 方法）对汇总流行率数据进行分析（95%置信区间[CI]）。共确定了 1072 篇文章。在去除重复项和排除文章后，有 61 篇文章用于偏倚评估。其中，有 19 篇低偏倚风险的文章被纳入综述和荟萃分析。分析中纳入的总人群为 15164 人，疫苗犹豫率为 30.5%（95%Cl：24.3-36.8%）。在疫苗接种开始前进行的研究中，疫苗犹豫率为 39.8%（95%Cl：31.4-48.2%），而在疫苗接种开始后进行的研究中，犹豫率为 20.4%（95%Cl：12.9-28%）。我们建议在不同人群中进行高质量的研究，以了解疫苗犹豫的程度，因为之前的许多研究主要集中在医护人员和学生，其余的都是基于社区的研究，这些研究普遍存在较高的偏倚。此外，我们建议早期接种疫苗可以降低疫苗犹豫。
