García Olazabal María Victoria, Moya Luis Eduardo Pascuali, Cirisola Rolf Wilhem Consolandich, Bruno Laura Hermida, Safi Federico Todeschini, Ando-Suguimoto Ellen Sayuri, Longo Priscila Larcher, Duran Cinthya Cosme Gutierrez, Bussadori Sandra Kalil, Motta Lara Jansiski, Fernandes Kristianne Porta Santos, Mesquita-Ferrari Raquel Agnelli, Horliana Anna Carolina Ratto Tempestini
Postgraduate Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), Rua Vergueiro, 239/245, São Paulo, SP, CEP 01504-000, Brazil.
Universidad Católica del Uruguay (UCU), Montevideo, Uruguay.
Clin Oral Investig. 2025 Jan 24;29(1):84. doi: 10.1007/s00784-025-06149-z.
To investigate if photobiomodulation (PBM) can reduce dentin hypersensitivity (DH) through a randomized, controlled, double-blind clinical trial.
One hundred and twelve patients experiencing DH after non-surgical scaling and root planing (SRP) were enrolled and divided into the Experimental Group - SRP + PBM (660 nm, 1.061 J/cm²) and the Control Group - SRP + PBM simulation. The primary outcome was the assessment of DH through tactile and thermal stimulation using the visual analog scale (VAS) after seven days. Additionally, paracetamol was prescribed and quantified as needed. Also, the impact of oral health on participants' quality of life using the Oral Health Impact Profile (OHIP-14) questionnaire was applied. Outcome assessments occurred seven days and one-month post-application.
In both 7 and 30 days, pain values were significantly lower in the experimental group compared to the control group (P = 0.001 and < 0.001, respectively). No differences were observed between the groups regarding analgesic usage. The experimental group also showed a significant improvement in the impact of oral health on participants' quality of life (P < 0.001), with lower OHIP-14 scores at all time points (P = 0.008).
These results suggest that photobiomodulation significantly reduces pain at 7- and 30-days following scaling and root planing. Additionally, it is associated with improvements in the oral health-related quality of life in patients with dentin hypersensitivity.
NCT05946265.
通过一项随机、对照、双盲临床试验，研究光生物调节（PBM）是否能降低牙本质过敏症（DH）。
招募112例在非手术龈下刮治和根面平整（SRP）后出现DH的患者，分为实验组——SRP + PBM（660 nm，1.061 J/cm²）和对照组——SRP + PBM模拟。主要结局是在7天后通过视觉模拟量表（VAS）使用触觉和热刺激评估DH。此外，根据需要开具并定量对乙酰氨基酚。还应用口腔健康影响程度量表（OHIP - 14）问卷评估口腔健康对参与者生活质量的影响。在应用后7天和1个月进行结局评估。
在7天和30天时，实验组的疼痛值均显著低于对照组（P分别为0.001和<0.001）。两组在镇痛药使用方面未观察到差异。实验组在口腔健康对参与者生活质量的影响方面也有显著改善（P < 0.001），在所有时间点OHIP - 14评分均较低（P = 0.008）。
这些结果表明，光生物调节在龈下刮治和根面平整后7天和30天时能显著减轻疼痛。此外，它与牙本质过敏症患者口腔健康相关生活质量的改善有关。
NCT05946265。
