Faussone-Pellegrini M S
Anat Embryol (Berl). 1985;171(2):163-9. doi: 10.1007/BF00341410.
The cytodifferentiation of the interstitial cells of Cajal (Type I) related to the myenteric plexus of the mouse intestinal muscle coat was studied in foetuses at term, neonates not yet fed, suckling animals, weaning animals and adult animals. In foetuses at term, interstitial cells of Cajal and their precursor cells are not identifiable. In neonates not yet fed, presumed precursor cells of the interstitial cells of Cajal, i.e. ICC-blasts, can be identified as cells surrounding the developing myenteric plexus and interposed between the circular and longitudinal muscle layers. These ICC-blasts are poorly differentiated but, like the adult interstitial cells, are always related to nerve endings and possess large and numerous mitochondria. In suckling animals these cells gradually develop, and are fully differentiated only after the end of the weaning period.
研究了足月胎儿、未进食的新生儿、哺乳期动物、断奶期动物和成年动物中与小鼠肠肌层肌间神经丛相关的Cajal间质细胞（I型）的细胞分化情况。在足月胎儿中，无法识别Cajal间质细胞及其前体细胞。在未进食的新生儿中，Cajal间质细胞的假定前体细胞，即ICC母细胞，可被识别为围绕发育中的肌间神经丛并介于环形肌层和纵形肌层之间的细胞。这些ICC母细胞分化程度低，但与成年间质细胞一样，总是与神经末梢相关，且拥有大量线粒体。在哺乳期动物中，这些细胞逐渐发育，仅在断奶期结束后才完全分化。
