Mlay Kenneth, Temba Gasper, Matasha Adrian, Mzonge Pendael, Katundu Denis, Chussi Desderius
Department of Medicine, Kilimanjaro Christian Medical University College, Moshi, Tanzania.
Department of Otorhinolaryngology, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.
Immun Inflamm Dis. 2025 Jan;13(1):e70130. doi: 10.1002/iid3.70130.
Allergic rhinitis is the specific inflammation against allergen by immune defense cells on the nasal mucosa, which can lead to chronic nasal symptoms such as sneezing, itching, runny nose, and nasal congestion. It is associated with high morbidity including sinusitis, asthma, otitis media, hypertrophied inferior turbinate, and nasal polyps. Despite its complications, it remains poorly recognized and tracked.
A cross-sectional hospital-based study was done, a total of 221 patients received Ear, Nose And Throat services at Kilimanjaro Christian Medical Center during the study period all patients with a clinical diagnosis of allergic rhinitis were captured; Data was collected using a pre-tested coded questionnaire (Score For Allergic Rhinitis). The data was then analyzed using SPSS version 22.
A total of 221 patients with a clinical diagnosis of allergic rhinitis were approached in a 6 months study period, 111 (50.2%) were females, and 140 (63.4%) were residing in urban areas. The prevalence of allergic rhinitis was 23.9%. Factors such as age OR 0.12, 95% CI (0.03; 0.40), education OR 0.13, 95% CI (0.04; 0.44), occupation OR 3.75, 95% CI (1.36; 10.32), adenotonsillar hypertrophy OR 4.66, 95% CI (2.21; 9.80), and OME OR 4.11, 95% CI (1.32; 12.83) (p = 0.009) were found to be significantly associated with allergic rhinitis. 60.4%, Inferior turbinate hypertrophy is the leading co-morbidity of allergic rhinitis which accounts for 64.7%.
Allergic rhinitis is among the common health problems affecting Tanzanians. It is a commonly seen disorder in younger age ( < 15 years) which is in correlation with other studies done in Africa and worldwide.
变应性鼻炎是鼻黏膜免疫防御细胞针对变应原产生的特异性炎症,可导致打喷嚏、瘙痒、流涕和鼻塞等慢性鼻部症状。它与鼻窦炎、哮喘、中耳炎、下鼻甲肥大和鼻息肉等高发病率疾病相关。尽管存在并发症,但对其认识和跟踪情况仍然较差。
进行了一项基于医院的横断面研究,在研究期间,共有221例患者在乞力马扎罗基督教医疗中心接受了耳鼻喉科服务,纳入了所有临床诊断为变应性鼻炎的患者;使用预先测试的编码问卷(变应性鼻炎评分)收集数据。然后使用SPSS 22版对数据进行分析。
在为期6个月的研究期间,共纳入221例临床诊断为变应性鼻炎的患者,其中111例(50.2%)为女性,140例(63.4%)居住在城市地区。变应性鼻炎的患病率为23.9%。年龄(比值比[OR]为0.12,95%置信区间[CI]为[0.03;0.40])、教育程度(OR为0.13,95%CI为[0.04;0.44])、职业(OR为3.75,95%CI为[1.36;10.32])、腺样体扁桃体肥大(OR为4.66,95%CI为[2.21;9.80])和中耳炎(OR为4.11,95%CI为[1.32;12.83])(p = 0.009)等因素被发现与变应性鼻炎显著相关。下鼻甲肥大是变应性鼻炎最主要的合并症,占64.7%,占变应性鼻炎合并症的60.4%。
变应性鼻炎是影响坦桑尼亚人的常见健康问题之一。它在较年轻年龄段(<15岁)较为常见,这与在非洲和全球开展的其他研究结果一致。