McMullin David R, Kirkland Anna K, Rehman Irbaz, Kovesi Thomas, Mallach Gary, Miller J David
Department of Chemistry, Carleton University, Ottawa, ON, Canada.
Department of Pediatrics, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Canada.
Int J Circumpolar Health. 2025 Dec;84(1):2457786. doi: 10.1080/22423982.2025.2457786. Epub 2025 Jan 24.
Rates of respiratory tract infections for children living in remote First Nations communities in the Sioux Lookout Zone in Northwestern Ontario are elevated and associated with poor indoor environmental quality including high exposures to endotoxin and serious dampness and mould damage. The studies also revealed a high prevalence of cigarette smoking and most houses have wood stoves, of variable quality. Depending on structure, polycyclic aromatic hydrocarbons (PAH) are carcinogens, immunotoxins and/or inflammatory mediators that are byproducts of the incomplete combustion of organic materials. Indoor sources of PAHs include tobacco smoke, cooking, and burning wood and/or fossil fuels for house heating. Twelve PAHs were measured in the <300 µm fraction of settled house dust by GC-MS in 59 houses. Nine PAHs were detected in all 59 houses, and median concentrations of individual PAHs measured ranged from 66 to 804 ng/g. PAHs associated with environmental tobacco smoke and with wood smoke dominated the PAH profile. Limiting tobacco smoking indoors and upgrading to low emission airtight wood stoves would improve indoor air quality and the respiratory health of children in this remote region of Ontario.
安大略省西北部苏圣洛区偏远原住民社区儿童的呼吸道感染率较高，且与室内环境质量差有关，包括内毒素暴露量高、严重潮湿和霉菌损害。研究还显示吸烟率很高，大多数房屋都有质量参差不齐的木炉。根据结构不同，多环芳烃（PAH）是有机材料不完全燃烧的副产物，属于致癌物、免疫毒素和/或炎症介质。室内多环芳烃的来源包括烟草烟雾、烹饪以及用于房屋取暖的木材和/或化石燃料燃烧。通过气相色谱 - 质谱联用仪（GC - MS）在59所房屋中小于300微米的沉降房屋灰尘中测量了12种多环芳烃。所有59所房屋中均检测出9种多环芳烃，所测单个多环芳烃的中位浓度范围为66至804纳克/克。与环境烟草烟雾和木烟相关的多环芳烃在多环芳烃谱中占主导地位。在安大略省这个偏远地区，限制室内吸烟并升级为低排放气密木炉将改善室内空气质量和儿童的呼吸健康。
