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新型青霉烯类抗生素Sch 34343的体外抗菌活性比较

Comparative in vitro antibacterial activity of Sch 34343, a novel penem antibiotic.

作者信息

Norrby S R, Jonsson M

出版信息

Antimicrob Agents Chemother. 1985 Jan;27(1):128-31. doi: 10.1128/AAC.27.1.128.

DOI:10.1128/AAC.27.1.128
PMID:3985593
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC176218/
Abstract

Using agar and broth dilutions, Sch 34343 was found to be highly active against gram-positive and gram-negative aerobic, facultatively anaerobic, and anaerobic bacteria, with the exceptions of enterococci, methicillin-resistant staphylococci, and Pseudomonas spp., which were resistant. Comparisons were made with imipenem, cefuroxime, cefotaxime, gentamicin, clindamycin, and metronidazole.

摘要

通过琼脂和肉汤稀释法发现,Sch 34343对革兰氏阳性和革兰氏阴性需氧菌、兼性厌氧菌及厌氧菌具有高活性,但肠球菌、耐甲氧西林葡萄球菌和假单胞菌属除外,这些菌对其耐药。并与亚胺培南、头孢呋辛、头孢噻肟、庆大霉素、克林霉素和甲硝唑进行了比较。

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Comparative in vitro antibacterial activity of Sch 34343, a novel penem antibiotic.新型青霉烯类抗生素Sch 34343的体外抗菌活性比较
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Clin Microbiol Rev. 1990 Jan;3(1):13-31. doi: 10.1128/CMR.3.1.13.

本文引用的文献

1
Comparative in-vitro activity of Sch 29482, a new penem antibiotic.新型青霉烯类抗生素Sch 29482的体外活性比较
J Antimicrob Chemother. 1982 Feb;9 Suppl C:31-40. doi: 10.1093/jac/9.suppl_c.31.
2
Oral absorption and tolerance in man, of a new penem antibiotic, Sch 29428.新型青霉烯类抗生素Sch 29428在人体中的口服吸收及耐受性
J Antimicrob Chemother. 1982 Feb;9 Suppl C:239-43. doi: 10.1093/jac/9.suppl_c.239.
3
In-vitro activity of Sch 29482 in comparison with other oral antibiotics.Sch 29482与其他口服抗生素相比的体外活性。
J Antimicrob Chemother. 1982 Feb;9 Suppl C:143-52. doi: 10.1093/jac/9.suppl_c.143.
4
Synthesis of Sch 29482--a novel penem antibiotic.新型青霉烯类抗生素Sch 29482的合成
J Antimicrob Chemother. 1982 Feb;9 Suppl C:1-5. doi: 10.1093/jac/9.suppl_c.1.
5
Sch 29482: in-vitro antibacterial activity and susceptibility to beta-lactamases.
J Antimicrob Chemother. 1982 Feb;9 Suppl C:25-30. doi: 10.1093/jac/9.suppl_c.25.