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不同类型蔬菜摄入量与代谢功能障碍相关脂肪性肝病之间的关联:一项基于人群的研究。

Associations between intake of different types of vegetables and metabolic dysfunction-associated fatty liver disease: a population-based study.

作者信息

Liu Chong, Liu Yubo, Liu Jie, Liu Jia, Lu Ting, Yu Jingjia, Zhang Guogang, Xu Kai

机构信息

Department of Cardiology, Third Xiangya Hospital, Central South University, Changsha, Hunan, China.

Department of Cardiovascular Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, China.

出版信息

BMC Public Health. 2025 Jan 24;25(1):315. doi: 10.1186/s12889-025-21331-4.

Abstract

BACKGROUND

Metabolic dysfunction-associated fatty liver disease (MAFLD) presently poses a threat to approximately 24% of the global population. The consumption of healthy diets rich in an abundant assortment of vegetables has been scientifically validated to mitigate the progression of MAFLD. However, it remains uncertain whether all categories of vegetables confer benefits for MAFLD. The objective of this study is to investigate the impact of different types of vegetables on MAFLD, aiming to provide a scientific basis for developing more appropriate dietary recommendations for individuals at high risk of MAFLD.

METHODS

We investigated the associations between various types of vegetable consumption and the risk of MAFLD, utilizing data sourced from the National Health and Nutrition Examination Survey (NHANES) 2017-2018 cycle. Employing multiple logistic regression and subgroup analyses, we estimated odds ratios (ORs) and 95% confidence intervals (CIs).

RESULTS

Our analysis encompassed a total of 3162 participants. Remarkably, heightened intake of dark green vegetables demonstrated an innovative association with reduced odds of MAFLD (OR = 0.54; 95% CI: 0.36-0.81; p-value = 0.01), while other kinds of vegetable shown no significant association with MAFLD in the full adjusted model (all p-vale > 0.05). In the subgroup analysis, a prominent inverse correlation between the consumption of dark green vegetables and MAFLD was discerned among female and non-Hispanic white people with higher educational attainment.

CONCLUSIONS

Our study conclusively demonstrates that a heightened intake of dark green vegetables is linked to diminished odds of MAFLD.

摘要

背景

代谢功能障碍相关脂肪性肝病(MAFLD)目前对全球约24%的人口构成威胁。科学验证表明,食用富含各种蔬菜的健康饮食可减轻MAFLD的进展。然而,尚不确定所有种类的蔬菜是否都对MAFLD有益。本研究的目的是调查不同类型蔬菜对MAFLD的影响,旨在为制定更适合MAFLD高危个体的饮食建议提供科学依据。

方法

我们利用2017 - 2018年国家健康与营养检查调查(NHANES)周期的数据,研究了各类蔬菜消费与MAFLD风险之间的关联。采用多元逻辑回归和亚组分析,我们估计了优势比(OR)和95%置信区间(CI)。

结果

我们的分析共纳入3162名参与者。值得注意的是,深绿色蔬菜摄入量的增加与MAFLD几率降低呈新的关联(OR = 0.54;95% CI:0.36 - 0.81;p值 = 0.01),而在完全调整模型中,其他种类的蔬菜与MAFLD无显著关联(所有p值 > 0.05)。在亚组分析中,在受教育程度较高的女性和非西班牙裔白人中,深绿色蔬菜消费与MAFLD之间存在显著的负相关。

结论

我们的研究最终表明,增加深绿色蔬菜的摄入量与降低MAFLD几率有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01be/11762863/528b3764a4e7/12889_2025_21331_Fig1_HTML.jpg

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