Life satisfaction includes various aspects, such as satisfaction with work, family, environment, and finances, and is influenced by sociodemographic and socioeconomic factors. This representative study investigates differential life satisfaction in the general population and its associations with sociodemographics. The study used a cross-sectional design with 2522 German participants, collected via face-to-face interviews and three-stage random sampling, assessing satisfaction across 17 life areas with the Differential Life Burden Scale. Overall life satisfaction was high ( = 4.46, scale from 1 to 6). Although globally satisfied, most participants (84.2%) named at least one negative area of life. Politics and environment were perceived as dissatisfying ( = 3.1; = 3.81, respectively); social contacts and leisure time were evaluated as rather satisfying ( about 5.00). Age, income, and unemployment were associated with life satisfaction. Gender and age were differently associated with life domains: Older people were less satisfied with their health. Younger people were more satisfied with leisure time. Younger were less satisfied with their children than older participants. The German population is generally satisfied with life, though factors like age, unemployment, and income influence the number of negatively perceived life domains. This highlights the importance of evaluating specific life areas in addition to overall life satisfaction for a more comprehensive understanding.